UniProt Accession

 DNJC5_RAT; P60905; P54101 

Genbank Protein ID

 U39320; S81917; AF323955 

Genbank Nucleotide ID

 AAA81372.1; AAB36303.1; AAL04453.1 

Protein Name

 DnaJ homolog subfamily C member 5 

Protein Synonyms/Alias

 Cysteine string protein; CSP 

Gene Name

 Dnajc5 

Gene Synonyms/Alias

 Csp 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
41	SYRKLALKYHPDKNP	ubiquitination	[1]
56	DNPEAADKFKEINNA	acetylation	[2]
56	DNPEAADKFKEINNA	ubiquitination	[1]
58	PEAADKFKEINNAHA	ubiquitination	[1]
72	AILTDATKRNIYDKY	ubiquitination	[1]

Reference

 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings. 

Sequence Annotation

 DOMAIN 13 82 J.
 MOD_RES 8 8 Phosphoserine (By similarity).
 MOD_RES 10 10 Phosphoserine (By similarity).
 MOD_RES 11 11 Phosphothreonine (By similarity).
 MOD_RES 12 12 Phosphoserine (By similarity).
 MOD_RES 15 15 Phosphoserine (By similarity).
 MOD_RES 17 17 Phosphotyrosine (By similarity).
 MOD_RES 56 56 N6-acetyllysine (By similarity).  

Keyword

 Acetylation; Cell membrane; Chaperone; Complete proteome; Direct protein sequencing; Lipoprotein; Membrane; Palmitate; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 198 AA 

Protein Sequence

Gene Ontology

 GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
 GO:0005886; C:plasma membrane; ISS:UniProtKB.
 GO:0008021; C:synaptic vesicle; IEA:Compara.
 GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Compara.
 GO:0007268; P:synaptic transmission; TAS:RGD. 

Interpro

 IPR001623; DnaJ_domain.
 IPR018253; DnaJ_domain_CS. 

Pfam

 PF00226; DnaJ 

SMART

 SM00271; DnaJ 

PROSITE

 PS00636; DNAJ_1
 PS50076; DNAJ_2 

PRINTS

 PR00625; JDOMAIN.