CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001112
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Microfibrillar-associated protein 3-like 
Protein Synonyms/Alias
 Testis development protein NYD-SP9 
Gene Name
 MFAP3L 
Gene Synonyms/Alias
 KIAA0626; HSD-39; HSD39 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
200EGAEKLQKAFEIAKRubiquitination[1, 2]
215IPIITSAKTLELAKVubiquitination[1, 2]
221AKTLELAKVTQFKTMubiquitination[1, 2]
226LAKVTQFKTMEFARYubiquitination[1, 2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
  
Sequence Annotation
 DOMAIN 47 141 Ig-like C2-type.
 CARBOHYD 33 33 N-linked (GlcNAc...) (Potential).
 CARBOHYD 37 37 N-linked (GlcNAc...) (Potential).
 CARBOHYD 67 67 N-linked (GlcNAc...) (Potential).
 CARBOHYD 111 111 N-linked (GlcNAc...) (Potential).
 CARBOHYD 135 135 N-linked (GlcNAc...) (Potential).
 DISULFID 68 125 Potential.  
Keyword
 Alternative splicing; Cell membrane; Complete proteome; Disulfide bond; Glycoprotein; Immunoglobulin domain; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 409 AA 
Protein Sequence
MDRLKSHLTV CFLPSVPFLI LVSTLATAKS VTNSTLNGTN VVLGSVPVII ARTDHIIVKE 60
GNSALINCSV YGIPDPQFKW YNSIGKLLKE EEDEKERGGG KWQMHDSGLL NITKVSFSDR 120
GKYTCVASNI YGTVNNTVTL RVIFTSGDMG VYYMVVCLVA FTIVMVLNIT RLCMMSSHLK 180
KTEKAINEFF RTEGAEKLQK AFEIAKRIPI ITSAKTLELA KVTQFKTMEF ARYIEELARS 240
VPLPPLIMNC RTIMEEIMEV VGLEEQGQNF VRHTPEGQEA ADRDEVYTIP NSLKRSDSPA 300
ADSDASSLHE QPQQIAIKVS VHPQSKKEHA DDQEGGQFEV KDVEETELSA EHSPETAEPS 360
TDVTSTELTS EEPTPVEVPD KVLPPAYLEA TEPAVTHDKN TCIIYESHV 409 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. 
Interpro
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR003598; Ig_sub2. 
Pfam
 PF07679; I-set 
SMART
 SM00408; IGc2 
PROSITE
 PS50835; IG_LIKE 
PRINTS