CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010522
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Glutathione peroxidase 2 
Protein Synonyms/Alias
 GPx-2; GSHPx-2; Glutathione peroxidase-gastrointestinal; GPx-GI; GSHPx-GI 
Gene Name
 Gpx2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
183INIEPDIKRLLKVAIacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
 ACT_SITE 40 40 By similarity.  
Keyword
 Complete proteome; Cytoplasm; Direct protein sequencing; Oxidoreductase; Peroxidase; Reference proteome; Selenocysteine. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 190 AA 
Protein Sequence
MAYIAKSFYD LSAIGLDGEK IDFNTFRGRA VLIENVASLU GTTTRDYTQL NELQCRFPRR 60
LVVLGFPCNQ FGHQENCQNE EILNSLKYVR HGGGFQPTFS LTQKCDVNGQ NQHPVFAYLK 120
DKLPYPYDDP FSLMTDPKLI IWSPVRRSDV SWNFEKFLIG PEGEPFRRYS RTFQTINIEP 180
DIKRLLKVAI 190 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004602; F:glutathione peroxidase activity; IDA:RGD.
 GO:0006979; P:response to oxidative stress; IEA:InterPro. 
Interpro
 IPR000889; Glutathione_peroxidase.
 IPR012336; Thioredoxin-like_fold. 
Pfam
 PF00255; GSHPx 
SMART
  
PROSITE
 PS00460; GLUTATHIONE_PEROXID_1
 PS00763; GLUTATHIONE_PEROXID_2
 PS51355; GLUTATHIONE_PEROXID_3 
PRINTS
 PR01011; GLUTPROXDASE.