UniProt Accession

 ECHD3_MOUSE; Q9D7J9; Q99LV0 

Genbank Protein ID

 AK009166; AL845275; AL928735; AL928735; AL845275; BC002214; BC054365 

Genbank Nucleotide ID

 BAB26117.1; CAM13700.1; CAM13700.1; CAM23671.1; CAM23671.1; AAH02214.1; AAH54365.1 

Protein Name

 Enoyl-CoA hydratase domain-containing protein 3, mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 Echdc3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
257	LGKATFYKQLPQDLR	acetylation	[1, 2]

Reference

 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Mitochondrion; Reference proteome; Transit peptide. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 300 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0003824; F:catalytic activity; IEA:InterPro. 

Interpro

 IPR001753; Crotonase_core_superfam. 

Pfam

 PF00378; ECH 

SMART

  

PROSITE

 PS00166; ENOYL_COA_HYDRATASE 

PRINTS