| Tag | Content |
|---|
| CPLM ID | CPLM-020887 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | General transcription factor IIE subunit 2 |
Protein Synonyms/Alias | Transcription initiation factor IIE subunit beta; TFIIE-beta |
Gene Name | Gtf2e2 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 75 | LSGSSGYKFGVLAKI | acetylation | [1] |
|
Reference | [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways. Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y. Mol Cell. 2013 Jun 27;50(6):919-30. [ PMID: 23806337] |
Functional Description | Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase (By similarity). |
Sequence Annotation | DNA_BIND 67 147 TFIIE beta. |
Keyword | Complete proteome; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 292 AA |
Protein Sequence | MDPSLLRDRE LFKKRALSTP VVEKRAVPSE SPSSSSSKKK KAKVEHGGSS GSKQNSDHNN 60
GSFNLKALSG SSGYKFGVLA KIVNYMKTRH QRGDTHPLTL EEILDETQHL DIGLKQKQWL 120
MTEALVNNPK IEVVDGKYAF KPKYNLKDKK ALLRLLDNHD QRGLGGILLE DIEEGLPNSQ 180
KAVKALGDQI LFVSRPDKKK ILFFNDKSCQ FSVDEEFQKL WRSVTVDSMD EEKIEEYLKR 240
QGISSMQESG PKKVASIQRR KKPASQKKRR FKTHNEHLAG VLKDYSDITP GK 292 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:Compara. GO:0005673; C:transcription factor TFIIE complex; IEA:InterPro. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006367; P:transcription initiation from RNA polymerase II promoter; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |