UniProt Accession

 ACK1_YEAST; Q07622; D6VRF1 

Genbank Protein ID

 X99000; Z74251; BK006938 

Genbank Nucleotide ID

 CAA67465.1; CAA98781.1; DAA11661.1 

Protein Name

 Activator of C kinase protein 1 

Protein Synonyms/Alias

  

Gene Name

 ACK1 

Gene Synonyms/Alias

 YDL203C; D1066 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
141	PFNFSSTKESLGSPA	ubiquitination	[1]
184	ESRILQEKVYRTEEK	ubiquitination	[1, 2, 3, 4, 5]
191	KVYRTEEKAPIRPLN	ubiquitination	[1, 5]
216	QPPTGSAKTDDNGSS	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] A proteomics approach to understanding protein ubiquitination.
 Peng J, Schwartz D, Elias JE, Thoreen CC, Cheng D, Marsischky G, Roelofs J, Finley D, Gygi SP.
 Nat Biotechnol. 2003 Aug;21(8):921-6. [PMID: 12872131]
 [3] Computational identification of ubiquitylation sites from protein sequences.
 Tung CW, Ho SY.
 BMC Bioinformatics. 2008 Jul 15;9:310. [PMID: 18625080]
 [4] Identification, analysis, and prediction of protein ubiquitination sites.
 Radivojac P, Vacic V, Haynes C, Cocklin RR, Mohan A, Heyen JW, Goebl MG, Iakoucheva LM.
 Proteins. 2010 Feb 1;78(2):365-80. [PMID: 19722269]
 [5] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 

Functional Description

  

Sequence Annotation

 REPEAT 318 361 Sel1-like 1.
 REPEAT 408 444 Sel1-like 2.
 REPEAT 495 531 Sel1-like 3.
 REPEAT 576 611 Sel1-like 4.
 CROSSLNK 184 184 Glycyl lysine isopeptide (Lys-Gly)  

Keyword

 Complete proteome; Isopeptide bond; Reference proteome; Repeat; Ubl conjugation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 623 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0031505; P:fungal-type cell wall organization; IMP:SGD.
 GO:0009967; P:positive regulation of signal transduction; IMP:SGD. 

Interpro

 IPR006597; Sel1-like.
 IPR011990; TPR-like_helical. 

Pfam

 PF08238; Sel1 

SMART

 SM00671; SEL1 

PROSITE

  

PRINTS