CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041643
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Leucine carboxyl methyltransferase 1 
Protein Synonyms/Alias
 RCG40565, isoform CRA_a 
Gene Name
 Lcmt1 
Gene Synonyms/Alias
 rCG_40565 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
179DLSELEEKLKKCNMNacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 REGION 169 170 S-adenosyl-L-methionine binding (By
 BINDING 71 71 S-adenosyl-L-methionine (By similarity).
 BINDING 96 96 S-adenosyl-L-methionine; via carbonyl
 BINDING 196 196 S-adenosyl-L-methionine; via carbonyl  
Keyword
 Complete proteome; Reference proteome; S-adenosyl-L-methionine. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 332 AA 
Protein Sequence
MATGSRESSF SSCASSCDFD DEGVRGTCED ASLCKRFAVS IGYWHDPYIE HLVRQSKERK 60
APEINRGYFA RVHGVSQLIK AFLRKTECRC QILNLGAGMD TTFWKLKDEG LLPNKYFEVD 120
FPMIVTRKLH TIKNKPLLFR PIMELHPEDT LQIDSHMLDS KRYAIIGADL RDLSELEEKL 180
KKCNMNTQLP TLLITECVLV YMTPEQSANL LKWAARSFET AMFINYEQVN MDDRFGQIMI 240
ENLRRRQCDL AGVETCKSLE SQKERLLLNG WETASAVNMM ELYSGLPRAE VNRIESLEFL 300
DEMELLEQLM RHYCLCWATR GGQELGLKEI TY 332 
Gene Ontology
 GO:0003880; F:protein C-terminal carboxyl O-methyltransferase activity; IEA:Compara. 
Interpro
 IPR007213; LCM_MeTrfase.
 IPR021121; LCM_MeTrfase_euk.
 IPR016651; Leu_CO_MeTrfase_LCTM1. 
Pfam
 PF04072; LCM 
SMART
  
PROSITE
  
PRINTS