CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028378
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CG13185, isoform B 
Protein Synonyms/Alias
  
Gene Name
 CG13185, Dmel_CG13185 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
40QKFIKKQKYVPQDVEacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Hydrolase; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 5303 AA 
Protein Sequence
MEVNVSKLRL GAQRLLELTA NESEDNVFSQ SLQKFIKKQK YVPQDVERLF RSLSEQLPLP 60
AYTVPIAASF EEQLLLLLSM ALRWDSASQR FHTYQLECVA LSKLMNFSLD AQRFAKSYFH 120
DKPAPFEKQQ SNGSLPSKKS KNGNHAADNL DDLELIKCCF QLLKSDTPYF RELWDWSSFI 180
ATYTHNSSSP KTQLYCNYIV AMLTNMSAPQ LNSLNEKIST KTRLEFDQER EQAWNTARNT 240
LCSYTPDASD QLLNLHLHGI NKSVTNIEGV LLPTFNEENL EFYASTDGCY DRIVKVDSTV 300
VNLRSIALGV AAAKPICLSG PVGCGKTTLI EYLARKTGRI CPKPNEIESR EKALKKAEEE 360
EQLLTPKKKA KTTGSKRKLE EVPLEELLDL GETTKKSGFL RIQLGDQTDS KMLLGQYRCT 420
DVPGEFVWLP GVLTQAVMHG YWLLLEDLDA ATQDTYTILS SLLERQCLSV PGFRDSVKIE 480
PGFQLFVTVR TNKSASNSSQ KSLYSLLDKY LYTINILPLS RNELCKMVSI NYPKLSTVAN 540
RIVDVFLTFS SGNHTSADNL RQQESGDKAD NTEQYVALPF EQVPLTSSPN SGRLVSTRDL 600
SKEKVTLITS IGAKLGIIRS RCEHFANEYK PDVEFGLEHI KIGRASLLAK SDLNNSENED 660
ISEQDLKRQK LSQQTRRAIG KVSNKRTTFS FTRLASCILE RIAVCVTHSE PVLLVGETGV 720
GKTSSVQYLA ERTEHKLVVV NMNNQSDVSD LVGGFKPVEL NYVLAPLRNE FEYLLCETFN 780
QEKNLQFLRL FATHYNSGRH AVIIRTMINI CLQVAKNPEL KANKLLPRWQ TLREKLQKLQ 840
MQLDKSINIS FAFIPGSLVN CISNGDWVLL DEINLASAET LECLSTILEP EGSVVLLERG 900
DFTPVKRHPD FRIFACMNPN TDIGKKDLPV GIRNRFTEFF VDELTTDADL SLLVSDYLAN 960
TGIQRKSVHN IVQLYKSLRK LSELQLNDGL GNRPVYSLRT LCRSLRICAR NLCGSIERNL 1020
YESFCLSFLT QLDPNSHHVV LLLIQNALLS NVKAILSKQL PQLGENYLDF EGYWIQPGNL 1080
EPQPCTHYIL TESVKKNLKD LARIISIGKL PILLQGPTSA GKTSLIDYVA RRSGNRCLRI 1140
NNHEHTDLQE YIGTYAADLD GKLTFREGVL VQAMRHGFWI ILDELNLAST DILEALNRVL 1200
DDNRELYIAE TQTLVKAHPN FMLFATQNPP GLYGGRKTLS RAFKNRFIEL HFADIPREEL 1260
ETILEKRCFI PPTYARKMVQ CMTQLQQHRK NTSKQVFTLR DLFRWGNRYT HADKSLHDDN 1320
RYDWNQHLVE EGYLVLSSKV RSQEEHELIE KTLFANFRKK LDLQTLFDIQ TDRESSSMVS 1380
RKILDAIRNF KLRDDIVWTR NMTRMAVVTA KALEFDEPVL LVGPTGCGKT TVCQLLASIA 1440
DVQLRILNCH MHTEGADFLG GLRPCRGKES TQLFEWADGP LIYAMQEGSY FMADEISLAE 1500
DSVLERLNCI LEPERTVLLA EKGGISELDA SPDFVVQAKS GFQFLATMNP GGDFGKKELS 1560
PALRNRFTEV WCLPSDNKED LIEIAYNCMR RQKEHENQAI NTHKVAEYLV DVVLHIRDTN 1620
DKFKFSVRDI LAWANYMVSN AKLSFAEQAI FGLETIFLDA LEMLPHESQE QVELLKSNIV 1680
KQAIKQASLI LQEKFTLEEL SEKRGTEVEL NECRFGIRPF FIDVNQERLT SAKEDFLFDA 1740
PTTKQNLFRL LSALSLQKPV LLEGPPGVGK TSIVESIGSA IGYQIVRINL CEHTDLADLF 1800
GTDLPAEDNL LESNTAATER QIRSFVWRDG PLLAALKAKN TWILLDELNL APQSVLEGLN 1860
AVLDHRGEVY IPELNKSFHL AGSTRIFACQ NPLKQGGGRK GLPQSFLNRF TKVYLRKLST 1920
EDLLHVVTEK YGKYFDQLNA YFLELLDQKA EGNLFEIYSG KESSCKSDSF DLGARLVRFS 1980
EQLDRGVASM EFGYKGGPYE FNLRDILRWC DLLHNPQTGY ILGASPSSFQ AAFKDFLLTL 2040
YERMQLVYYQ RMRCDQDKSY IRNVFSTVFL CDAEYLNQVS NDVALYWTAD KVYLNDVVLS 2100
RKQADVLDLV NRQEQSPLLL DSQRQQLKQI IETVHMEKPL LLCGSTDSGK TKLIDALCVL 2160
SNRLCNTDII DDSVTGSFQQ HMFSEAQQHS VLDELKLFSE RLGSLGKIIE VLEATPQNCQ 2220
VRALQQLAEI KSQLLLLQTY IKTADSLNTG GSFEWVDSQI VTSLKCGQYI LLEHVNLCSS 2280
AVLDRLNPVF EPNGSLLIAE KGISAQDSAE VVYKSTNFRA FLTVDPKNGE LSRAMRNRCV 2340
ELSLSRDTYS VDDLRAFVHE QGVREMEAID CILRVHKGLS QLTEFNNYSI SHLTQFAFLS 2400
AAYRRIGYEL KRAIYVAAME VYVYSANTDL MGYGLSYYQN KLREVVLAQT EVFEEVAVIQ 2460
EDFLSDVILN SGNLNSLTLI KRQAVALKVL LDGYTEGKIP QKLLASLFHE MEKLKLDQRN 2520
PQKLIRHFLY MLYESSAIGD LELRHLYLQP WLSKDTAFQE LSQNLYNCLQ KRSNTDTGTL 2580
ANLPWNRKLI PRLRDYSTAE SNSELNPLNL SALLLARLVV DIIPVSSVTT VQQMNALQYS 2640
QALSKSGCAR MLTIQDRTLK IKKYIEETRR PLNVTCKIYS KQFTQFQPYY QDQQIQRHIE 2700
LDDLEKLLSV VPSYGNLELS SWLKRWLLLQ TDDANKWRSF LRKHTNGFQP KAFEISGSLR 2760
NETLQSHLQK LQTTLKEAQE NSAEIEMDLE LDLNSIKTLL EAETEESESY IHPDGIPTNT 2820
PKLLIAALRE LFMERLLTGT LRDDFDEQVN PLYADQLLTL NSNLWHCLKT LESANRTEIT 2880
NAWIELKNEV NELQNYDEFA VLLEKIGGGY KGLRSYQRQY RNSVQCYQLE NLSTRLDCVQ 2940
GPSEEGSTDI SSQFCYRGPA LSGVILSLIC QPNGQLRSVP LSELLEWRSA LQQTRHLIWE 3000
NSQLLTSRYS GEVNNLLQAK ENARQLLKEL EYVRKLSEKE QKANQGFENC AKELEKMIEK 3060
LEKEENNNAS MTKDFEVSLT NALVGAIELC LLTNTPLIDP VEKNRLKNEY IAEDIDCLST 3120
LTTAYDFMKI AMKYRHFGEE IYSELELRLR TALQRQQQLS QKLALRSEKC LYASLVQDIT 3180
HFLHSNGDCE SLYKLFQLIH SEWENFQGLH VATSAQLKSS IEVLGKLDLW LANAQRFVHH 3240
TLSRYSAYYQ DFVEPIKCSV NQLRFGLESL KVIFTRVQQA GSVSQAEQMQ QTIGDIVQFP 3300
SQHPLVIRNS RLYGLLAELP HSEYEYFRLL KAKLSELSNY IALGRVIDET TFAAYDDALS 3360
ICNQTWQQEE HRRCQLKAEA ESLYVTKTKG GVDSEELIEM QEIEHNFPTN LDEDFAEFVS 3420
QPTLEQVLKL DKKASAKDKQ SQIVVEEDYA FLARNFIDVM TRHTQVYYKE QPKSSKELEL 3480
HLLAPYQARF QVFANLHGHY KTALGSSLEE RACNGLAFGL ALQQKQLRDI ELEEGVSSSP 3540
YDFYKDSNIS EIQSCLDVME RIEKRVLEQL EQYPEHAGLA DIKLVISRIR RLPAHAPVVR 3600
FNTGFQLLRQ KLALWNEVAH RNNNLVSEEI EVAEFVQRWT RLELQHWRNC LGQTAAQVEL 3660
QAYRYWFFIY NLLQQFIHQK QLDHSYTDIK LAEQRFAQDH LLDAQDLGES QRLELAQVVR 3720
ILRQFVEASC YGDFHIRLQL LQGFELYLHN VERAGKINGL PPLIAALHNL QLYFSQFAGE 3780
IADSAKLRRS PIEKKLKEFV KIQSYSKDLS YFSMRNSVAS VHRNLNKFLK EYRLSIQEKI 3840
SEVFQPKDST AKDYTFGTDK GKGLRNYNKI KYLHTERQQF VASEKLLEKF AIQEEFLSDN 3900
TLLQRLDKHF RTARHVVKET LGQVPYGELI TELDDLLASQ LERCEHLRSL NVDRSKERPQ 3960
QKQEAKQILQ QKRKALTDLF KMLHRLGANY KTGLLELSLR NEFEDFQLPP YSIRSMLPRL 4020
HPTAQQLDEH LDLYYMKSVF KLKLLQNIML TPLSELGPPN IERIKGFAVD LFLLVQQQRE 4080
HLSGSTKELH ELRNSLDSLR KLAEIIPQAD INPSTLNFVK SADIAMEIKQ HLRQIHYVLK 4140
QWKLLLSCAP SSFIEESENR LLILNSSQEL LNELNNANLE YLSSEKCVTY QKSYAEIQEN 4200
IKKTLELLRT GQNDYLPLAQ PIVELLDSVQ LKNHTEIAPE AIDLANADTE LANIAHSVLM 4260
SMQKIYKHHV KTDEVNQNGE AKEQDEESKE ALQEQHLKKC LTGELTSDWQ QLSLPRVLGK 4320
LSNVLLVLKH SHFEGKDKLL CLATHKVSAK MLSIVLTVFV EIGSKGFCVP PDLMQDEEGQ 4380
SKQESKNGEG FGLEDGTGEN DASDKIESED QLDDAKRPED RKDEGDKQEP DCKEEKGIEM 4440
SDDFDAKMQD VEKPEEDDSG ESEEEEDLNK EMGETEEGAE KLDDQIWGDD EEEKPEEEQE 4500
PDMNEEDQGK GSKDEKDAHN DLDTKNDAAK EDGKDEHEKD GLDATNEPSG EDKRKEQAKD 4560
IDDMKDPEMD EEQTNAMHNE LEEPPEPEEM DLGDMNNVDE GHDDQDEQPT DENPFDIDAM 4620
KENMQPAEEP EADGDDEHDA NEEGDPQSDG SDSEEDEAGT EAKPAEEDHG EGEEATPEDE 4680
KDEAETQKRG ELEDEDDSKP EDSPEDSKEE KEEKREEKPE EHSQSKDKAS KEENVQSMPE 4740
TDQSSSADQV QQPQDPDIKQ DQKLDEQETG EEKDGVGQAE NDADDGGHQG VAETQETVSQ 4800
EDRKNERQTQ EKRKQGRTNE ERSLGEAEQN KLKQLKTIDQ LKDSKESDDA EQEKPEPMDQ 4860
TEAEEYQHVK EPKNSDKTTL DNATEEQSKK IQHQEDEPPN EEEIEAENVD ELMEAEEPAV 4920
DPEDDAELEQ LGAEKTEQKS DKPSKTEKSK EQLETPEGME IEGEVVLTMT VPRSSETTAH 4980
SNSEILLDKS SHAEDLSSAE QIELRQQYQK QLTTFRVAQP EHEDYETWQG ISNRMTQNAR 5040
ELCEQLRLIL EPTKCTRLKG DYRTGRRINM KKIIPYIASQ FRKDKIWLRR TKPAQRDYKI 5100
TIAIDDSKSM HHNNSKTLTL EAISLVSQAL TLLESGRLSI VSFGEAPQII LNHTEQFDGP 5160
RLVNALNFAQ DKTKIAGLLN FIRTANAEES GTGGDNGLFE NLLLILSDGR NIFSEGAQNV 5220
KNAIKLARLQ RIFLVYIIID NPDNKNSILD IQHVAVNADG SVNINSYLDS FPFPYYVIVR 5280
DLNQLPLVLS EAMRQWFELV NSE 5303 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:EC.
 GO:0006200; P:ATP catabolic process; IEA:GOC. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR011704; ATPase_dyneun-rel_AAA.
 IPR027417; P-loop_NTPase.
 IPR002035; VWF_A. 
Pfam
 PF07728; AAA_5 
SMART
 SM00382; AAA
 SM00327; VWA 
PROSITE
 PS50234; VWFA 
PRINTS