CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-013715
UniProt Accession
ARLY_GEOKA
;
Q5KW95
Genbank Protein ID
BA000043
Genbank Nucleotide ID
BAD77041.1
Protein Name
Argininosuccinate lyase
Protein Synonyms/Alias
ASAL; Arginosuccinase
Gene Name
argH
Gene Synonyms/Alias
GK2756
Created Date
July 27, 2013
Organism
Geobacillus kaustophilus (strain HTA426)
NCBI Taxa ID
235909
Lysine Modification
Position
Peptide
Type
References
283
GSSIMPQ
K
KNPDMAE
acetylation
[1]
Reference
[1] Proteomic analysis of acetylation in thermophilic Geobacillus kaustophilus.
Lee DW, Kim D, Lee YJ, Kim JA, Choi JY, Kang S, Pan JG.
Proteomics. 2013 Aug;13(15):2278-82. [
PMID: 23696451
]
Functional Description
Sequence Annotation
Keyword
Amino-acid biosynthesis; Arginine biosynthesis; Complete proteome; Cytoplasm; Lyase.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
459 AA
Protein Sequence
MKKLWGGRFT KTAEEWVDEF GASIPFDQEL VEEDIEGSLA HVTMLGECGI LPEGDVEQIK 60
GGLIRLLEKA KQGELKFSIA YEDIHLNIEK MLIDDIGPVG GKLHTGRSRN DQVATDMHLY 120
LRKRVEEILG LIRGMQRALV AQAEKHVETI MPGYTHLQRA QPISFAHHLL AYFWMLERDY 180
ERFSESQKRI NRSPLGAGAL AGTTFPIDRH RTAELLGFAD IYENSLDAVS DRDFIIEFLS 240
NSSMLMMHLS RLAEELILWS SQEFQFIELD DAFATGSSIM PQKKNPDMAE LIRGKTGRVY 300
GHLMALLTVM KGLPLAYNKD MQEDKEGMFD TVKTVIGSLK IFTGMIETMN VRTDVMERAT 360
KQDFSNATEL ADYLAAKGVP FREAHEIVGK LVLHCIEQGV FLADLPLDVY KEASPLFEED 420
IYDALHPRTA VNRRNSAGGT GFAEVRAALA KAKQLLSTP 459
Gene Ontology
GO:0005737
; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004056
; F:argininosuccinate lyase activity; IEA:HAMAP.
GO:0042450
; P:arginine biosynthetic process via ornithine; IEA:InterPro.
Interpro
IPR009049
; Argininosuccinate_lyase.
IPR003031
; D_crystallin.
IPR024083
; Fumarase/histidase_N.
IPR000362
; Fumarate_lyase.
IPR020557
; Fumarate_lyase_CS.
IPR022761
; Fumarate_lyase_N.
IPR008948
; L-Aspartase-like.
Pfam
PF00206
; Lyase_1
SMART
PROSITE
PS00163
; FUMARATE_LYASES
PRINTS
PR00145
; ARGSUCLYASE.
PR00149
; FUMRATELYASE.