CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024070
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nuclear pore complex protein Nup160 
Protein Synonyms/Alias
 160 kDa nucleoporin; Gene trap locus 1-13 protein; GTL-13; Nucleoporin Nup160 
Gene Name
 Nup160 
Gene Synonyms/Alias
 Gtl1-13; Kiaa0197 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
574RDVLCLIKCLRMIGEacetylation[1]
931PKLQYYDKVLRLLDVubiquitination[2]
1381LSQKILDKLEDYQQKacetylation[3]
1381LSQKILDKLEDYQQKubiquitination[2]
1388KLEDYQQKVDKATRDubiquitination[2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
 Involved in poly(A)+ RNA transport. 
Sequence Annotation
 MOD_RES 1123 1123 Phosphoserine.
 MOD_RES 1161 1161 Phosphothreonine.  
Keyword
 Alternative splicing; Complete proteome; mRNA transport; Nuclear pore complex; Nucleus; Phosphoprotein; Protein transport; Reference proteome; Translocation; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1402 AA 
Protein Sequence
MAAAGSLERS FVELSGAERE RPRHFREFTV CDIGTASAAF GTVKYSESAG GFYYVESGKL 60
FSITRNRFIH WKTSGDTLEL VEESLDLNLL NNAVRLKFQN YNILPGGVHV SETQNHVIIL 120
ILTNQTVHRL ILPHPSRMYR SELVTESQMQ SIFTDIGKVD FRDPCNSQLI PSVPGLSPGS 180
TTSAAWLSSD GEALFALPSA SGGIFVLKLP PYDVPGIASV VELKQSSVMQ RLLTGWMPTA 240
IRGDHGPSDR ALSLAVHCVE HDAFIFALCQ DHKLRMWSYK DQMCLMVADM LEYVPVNKDL 300
RLTAGTGHKL RLAYSPSMGL YLGIYMHAPK RGQFCVFQLV STENNRYSLD HISSLFTSQE 360
TLVDFALTST DIWALWHDAE NQTIVKYINF EHNVAGQWNP VFMQPLPEEE IVIRDDQDPR 420
EMYLRSLFTP GHFINAALCK ALQIFCRGTE RNLDLSWNEL KKEITLAVEN ELQGSVTEYE 480
FSQDEFRTLQ QEFWCKFYAC VLQYQEALSH PLALHLNPVT NMVCLLKKGY LSFLVPSSLV 540
DHLYLLPDEH LLTEDETTIS DDADVARDVL CLIKCLRMIG ESVTMDMAVL METSCYNLQS 600
PEKAAEHILE DLITIDVENV MEDICSKLQE IRNPVHAIGL LIREMDYETE VEMEKGFDPA 660
QPLNVRMNLS QLYGSSTAGY IVCRGVYKIA STRFLICRDL LILQQLLTRL GDAVILGAGQ 720
LFQAQQDLLH RTAPLLLSYY LIKWASQCLA TDVPVDTLES NLQHLSVLEL TDSGALMANK 780
LVSSPQTIME LFFQEVARKQ IISHLFSQPK APLSQTGLNW PEMITAVTGY LLQLLWPSNP 840
GCLFLECLMG NCQYVQLQDY IQLLHPWCQV NVGSCRFMLG RCYLVTGEVQ KALECFCQAA 900
SEVGKEEFLD RLIRSEDGEI VSTPKLQYYD KVLRLLDVVG LPELVIQLAT SAITEAGDDW 960
KSQATLRTCI FKHHLDLGHN SQAYEALTQI PDSSRQLDCL RQLVVVLCER SQLQDLVEFP 1020
YVNLHNEVVG IIESRARAVD LMTHNYYELL YAFHIYRHNY RKAGTVMFEY GMRLGREVRT 1080
LRGLEKQGNC YLAAINCLRL IRPEYAWIVQ PASGAVSDRP GASPKRNHDG ECTAAPTNRQ 1140
IEILELEDLE KEYSLARIRL TLARHDPSVI AIAGSSSAKE MSALLVQAGL FDTAISLCQT 1200
FTLPLTPVFE GLAFKCIKLQ FGGEAAQGEA WSWLATNQLS SVITTKESSA TDEAWRLLST 1260
YLERYKVQNN LYHHCVINKL LSHGVPLPNW LINSYKKVDA AELLRLYLNY DLLEEAVDLV 1320
SEYVDAVLGK GHQYFGIEFP LSATAPMVWL PYSSIDQLLQ ALGENSANSH NIILSQKILD 1380
KLEDYQQKVD KATRDLLYRR DL 1402 
Gene Ontology
 GO:0000776; C:kinetochore; IEA:Compara.
 GO:0031080; C:nuclear pore outer ring; ISS:UniProtKB.
 GO:0005487; F:nucleocytoplasmic transporter activity; IDA:UniProtKB.
 GO:0006406; P:mRNA export from nucleus; IDA:UniProtKB.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR021717; Nucleoporin_Nup160. 
Pfam
 PF11715; Nup160 
SMART
  
PROSITE
  
PRINTS