UniProt Accession

 B1ATI0_MOUSE; B1ATI0 

Genbank Protein ID

 AL646093; AL672172 

Genbank Nucleotide ID

  

Protein Name

 Fatty aldehyde dehydrogenase 

Protein Synonyms/Alias

  

Gene Name

 Aldh3a2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
39	RMVQEREKEILAAIA	ubiquitination	[1]
262	NQIVQKIKETVKDFY	ubiquitination	[1]
266	QKIKETVKDFYGENI	acetylation	[2, 3]
274	DFYGENIKASPDYER	acetylation	[3]
274	DFYGENIKASPDYER	ubiquitination	[1]
296	KRLQSLLKGQKIAFG	acetylation	[3]
296	KRLQSLLKGQKIAFG	ubiquitination	[1]
299	QSLLKGQKIAFGGEM	ubiquitination	[1]
357	NFINDREKPLALYVF	ubiquitination	[1]
369	YVFSRNNKLIKRVID	acetylation	[3]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [3] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 532 AA 

Protein Sequence

Gene Ontology

 GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
 GO:0004030; F:aldehyde dehydrogenase [NAD(P)+] activity; IEA:InterPro.
 GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro. 

Interpro

 IPR016161; Ald_DH/histidinol_DH.
 IPR016163; Ald_DH_C.
 IPR016160; Ald_DH_CS.
 IPR016162; Ald_DH_N.
 IPR015590; Aldehyde_DH_dom.
 IPR012394; Aldehyde_DH_NAD(P). 

Pfam

 PF00171; Aldedh 

SMART

  

PROSITE

 PS00070; ALDEHYDE_DEHYDR_CYS
 PS00687; ALDEHYDE_DEHYDR_GLU 

PRINTS