CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042703
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein virilizer homolog 
Protein Synonyms/Alias
  
Gene Name
 KIAA1429 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
240KADENNAKLQELGKWubiquitination[1]
246AKLQELGKWLEPLKNubiquitination[2]
252GKWLEPLKNLRFEINubiquitination[1, 3, 4]
382RGGSFEFKDMRVPSAubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 730 AA 
Protein Sequence
QPVKSFPTMA RITGPPERDD PYPVLFRYLH SHHFLELVTL LLSIPVTSAH PGVLQATKDV 60
LKFLAQSQKG LLFFMSEYEA TNLLIRALCH FYDQDEEEGL QSDGVIDDAF ALWLQDSTQT 120
LQCITELFSH FQRCTASEET DHSDLLGTLH NLYLITFNPV GRSAVGHVFS LEKNLQSLIT 180
LMEYYSKEAL GDSKSKKSVA YNYACILILV VVQSSSDVQM LEQHAASLLK LCKADENNAK 240
LQELGKWLEP LKNLRFEINC IPNLIEYVKQ NIDNLMTPEG VGLTTALRVL CNVACPPPPV 300
EGQQKDLKWN LAVIQLFSAE GMDTFIRVLQ KLNSILTQPW RLHVNMGTTL HRVTTISMAR 360
CTLTLLKTML TELLRGGSFE FKDMRVPSAL VTLHMLLCSI PLSGRLDSDE QKIQNDIIDI 420
LLTFTQGVNE KLTISEETLA NNTWSLMLKE VLSSILKVPE GFFSGLILLS ELLPLPLPMQ 480
TTQVIEPHDI SVALNTRKLW SMHLHVQAKL LQEIVRSFSG TTCQPIQHML RRICVQLCDL 540
ASPTALLIMR TVLDLIVEDL QSTSEDKEKQ YTSQTTRLLA LLDALASHKA CKLAILHLIN 600
GTIKGDERYA EIFQDLLALV RSPGDSVIRQ QCVEYVTSIL QSLCDQDIAL ILPSSSEGSI 660
SELEQLSNSL PNKELMTSIC DCLLATLANS ESSYNCLLTC VRTMMFLAEH DYGLFHLKRD 720
AVEMIMVSWK 730 
Gene Ontology
  
Interpro
 IPR026736; Virilizer. 
Pfam
  
SMART
  
PROSITE
  
PRINTS