CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044296
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 Gm5422 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
89TSMTSVPKPLKFLRPubiquitination[1]
102RPHYGKLKEIYENMAacetylation[2]
102RPHYGKLKEIYENMAubiquitination[1]
173QELDDAEKAQREPLLubiquitination[1]
338ELDIMEPKVPDDIYKacetylation[3]
338ELDIMEPKVPDDIYKubiquitination[1]
345KVPDDIYKTHLENNRacetylation[3]
345KVPDDIYKTHLENNRubiquitination[1]
392LLTDDGNKWLYKNKDacetylation[3]
392LLTDDGNKWLYKNKDubiquitination[1]
853DVVGQAGKPKTITGFubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 903 AA 
Protein Sequence
MRQDTRVVPT ALRDHPQLRG REVARSEGMR GRGAGEEQEL SEVDKQLQDE LEMLLERLRE 60
KDTSLYRPAL EELRRQIHSS TTSMTSVPKP LKFLRPHYGK LKEIYENMAP GENKCFAADI 120
ISVLAMTMSG ERECLKYRLV GSQEELASWG HEYVRHLAGE VTKEWQELDD AEKAQREPLL 180
TLVKEIVPYN MAHNAEHEAC DLLMEIEQVD VLEKDIDENA YAKVCLYLTS CVNYLPEPEN 240
SALLRCALRM FRKFSRFPES LRLALMLNDM ELVEDIFTSC KDVVVQKQMA SMLARRGVFL 300
ELSEDVEEYE DLTEIMSNVQ LNSNFLALAR ELDIMEPKVP DDIYKTHLEN NRFGSSGSQV 360
DSARMNLASS FVNGFVNAAF GQDKLLTDDG NKWLYKNKDH GMLSAAASLG MILLWDVDGG 420
LTQIDKYLYS SEDYIKSGAL LACGIVNSGV QNECDPALAL LSDYVLHNSN TMRLGSIFGL 480
GLAYAGSNRE DVLTLLLPVM GDSKSSMEVA GVTALACGMI AVWSCNGDVT STILQTIMEN 540
YKTELKDTCA RWLPLGLGLN HLGKGEAIEA ILADLEVVSE PFRSFANTLV DVCAYAGSGN 600
VLTVQQLLHI CSEHFDSKEK EEDKNKKVKK DKGKKDVPAA MGAHQGAAVL GIALTALGEE 660
IGAEMALRTF GHLLRYGEPT LCRAVPLALA LTSVSNPRLN ILDTLSKFSH DADPEVSYNS 720
IFAMSMVGRG TNNARLAAML RQLAQHHAKD PNNLFMVRLA QGLTHLGKGT LTLCPYHTDR 780
QLMSQVAVAG LLTVLVSFLD VRNIILGKSH YVLYRLVAAM QPRMLVTFDE ELRPLPVSVR 840
VGQAVDVVGQ AGKPKTITGF QTHTMSVLLA QGERAELATE EFLPVTSILE GFVILRKNPN 900
YDL 903 
Gene Ontology
 GO:0000502; C:proteasome complex; IEA:InterPro.
 GO:0030234; F:enzyme regulator activity; IEA:InterPro.
 GO:0050790; P:regulation of catalytic activity; IEA:GOC.
 GO:0042176; P:regulation of protein catabolic process; IEA:InterPro. 
Interpro
 IPR016643; 26S_Psome_Rpn1.
 IPR002015; APC_proteasome.
 IPR016024; ARM-type_fold. 
Pfam
 PF01851; PC_rep 
SMART
  
PROSITE
  
PRINTS