Tag | Content |
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CPLM ID | CPLM-037383 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Dystonin |
Protein Synonyms/Alias | |
Gene Name | DST |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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50 | QKGRHPMKSVFSGRS | ubiquitination | [1] | 362 | TTCWRDGKLFNAIIH | ubiquitination | [1] | 3450 | EKRGITSKVLPLQLE | ubiquitination | [1] |
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Reference | [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C. Nat Cell Biol. 2012 Oct;14(10):1089-98. [ PMID: 23000965] |
Functional Description | |
Sequence Annotation | |
Keyword | Actin-binding; Calcium; Complete proteome; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 7750 AA |
Protein Sequence | MIAAAFLVLL RPYSIQCALF LLLLLLGTIA TIVFFCCWHR KLQKGRHPMK SVFSGRSRSR 60 DAVLRSHHFR SEGFRASPRH LRRRVAAAAA ARLEEVKPVV EVHHQSEQET SVRKRRIKKS 120 SRVQPEFYHS VQGASIRRPS SGNASYRCSM SSSADFSDED DFSQKSGSAS PAPGDTLPWN 180 LPKHERSKRK IQGGSVLDPA ERAVLRIADE RDKVQKKTFT KWINQHLMKV RKHVNDLYED 240 LRDGHNLISL LEVLSGDTLP REKGRMRFHR LQNVQIALDY LKRRQVKLVN IRNDDITDGN 300 PKLTLGLIWT IILHFQISDI HVTGESEDMS AKERLLLWTQ QATEGYAGIR CENFTTCWRD 360 GKLFNAIIHK YRPDLIDMNT VAVQSNLANL EHAFYVAEKI GVIRLLDPED VDVSSPDEKS 420 VITYVSSLYD AFPKVPEGGE GIGANDVEVK WIEYQNMVNY LIQWIRHHVT TMSERTFPNN 480 PVELKALYNQ YLQFKETEIP PKETEKSKIK RLYKLLEIWI EFGRIKLLQG YHPNDIEKEW 540 GKLIIAMLER EKALRPEVER LEMLQQIANR VQRDSVICED KLILAGNALQ SDSKRLESGV 600 QFQNEAEIAG YILECENLLR QHVIDVQILI DGKYYQADQL VQRVAKLRDE IMALRNECSS 660 VYSKGRILTT EQTKLMISGI TQSLNSGFAQ TLHPSLTSGL TQSLTPSLTS SSMTSGLSSG 720 MTSRLTPSVT PAYTPGFPSG LVPNFSSGVE PNSLQTLKLM QIRKPLLKSS LLDQNLTEEE 780 INMKFVQDLL NWVDEMQVQL DRTEWGSDLP SVESHLENHK NVHRAIEEFE SSLKEAKISE 840 IQMTAPLKLT YAEKLHRLES QYAKLLNTSR NQERHLDTLH NFVSRATNEL IWLNEKEEEE 900 VAYDWSERNT NIARKKDYHA ELMRELDQKE ENIKSVQEIA EQLLLENHPA RLTIEAYRAA 960 MQTQWSWILQ LCQCVEQHIK ENTAYFEFFN DAKEATDYLR NLKDAIQRKY SCDRSSSIHK 1020 LEDLVQESME EKEELLQYKS TIANLMGKAK TIIQLKPRNS DCPLKTSIPI KAICDYRQIE 1080 ITIYKDDECV LANNSHRAKW KVISPTGNEA MVPSVCFTVP PPNKEAVDLA NRIEQQYQNV 1140 LTLWHESHIN MKSVVSWHYL INEIDRIRAS NVASIKTMLP GEHQQVLSNL QSRFEDFLED 1200 SQESQVFSGS DITQLEKEVN VCKQYYQELL KSAEREEQEE SVYNLYISEV RNIRLRLENC 1260 EDRLIRQIRT PLERDDLHES VFRITEQEKL KKELERLKDD LGTITNKCEE FFSQAAASSS 1320 VPTLRSELNV VLQNMNQVYS MSSTYIDKLK TVNLVLKNTQ AAEALVKLYE TKLCEEEAVI 1380 ADKNNIENLI STLKQWRSEV DEKRQVFHAL EDELQKAKAI SDEMFKTYKE RDLDFDWHKE 1440 KADQLVERWQ NVHVQIDNRL RDLEGIGKSL KYYRDTYHPL DDWIQQVETT QRKIQENQPE 1500 NSKTLATQLN QQKMLVSEIE MKQSKMDECQ KYAEQYSATV KDYELQTMTY RAMVDSQQKS 1560 PVKRRRMQSS ADLIIQEFMD LRTRYTALVT LMTQYIKFAG DSLKRLEEEE KSLEEEKKEH 1620 VEKAKELQKW VSNISKTLKD AEKAGKPPFS KQKISSEEIS TKKEQLSEAL QTIQLFLAKH 1680 GDKMTDEERN ELEKQVKTLQ ESYNLLFSES LKQLQESQTS GDVKVEEKLD KVIAGTIDQT 1740 TGEVLSVFQA VLRGLIDYDT GIRLLETQLM ISGLISPELR KCFDLKDAKS HGLIDEQILC 1800 QLKELSKAKE IISAASPTTI PVLDALAQSM ITESMAIKVL EILLSTGSLV IPATGEQLTL 1860 QKAFQQNLVS SALFSKVLER QNMCKDLIDP CTSEKVSLID MVQRSTLQEN TGMWLLPVRP 1920 QEGGRITLKC GRNISILRAA HEGLIDRETM FRLLSAQLLS GGLINSNSGQ RMTVEEAVRE 1980 GVIDRDTASS ILTYQVQTGG IIQSNPAKRL TVDEAVQCDL ITSSSALLVL EAQRGYVGLI 2040 WPHSGEIFPT SSSLQQELIT NELAYKILNG RQKIAALYIP ESSQVIGLDA AKQLGIIDNN 2100 TASILKNITL PDKMPDLGDL EACKNARRWL SFCKFQPSTV HDYRQEEDVF DGEEPVTTQT 2160 SEETKKLFLS YLMINSYMDA NTGQRLLLYD GDLDEAVGML LEGCHAEFDG NTAIKECLDV 2220 LSSSGVFLNN ASGREKDECT ATPSSFNKCH CGEPEHEETP ENRKCAIDEE FNEMRNTVIN 2280 SEFSQSGKLA STISIDPKVN SSPSVCVPSL ISYLTQTELA DISMLRSDSE NILTNYENQS 2340 RVETNERANE CSHSKNIQNF PSDLIENPIM KSKMSKFCGV NETENEDNTN RDSPIFDYSP 2400 RLSALLSHDK LMHSQGSFND THTPESNGNK CEAPALSFSD KTMLSGQRIG EKFQDQFLGI 2460 AAINISLPGE QYGQKSLNMI SSNPQVQYHN DKYISNTSGE DEKTHPGFQQ MPEDKEDESE 2520 IEEYSCAVTP GGDTDNAIVS LTCATPLLDE TISASDYETS LLNDQQNNTG TDTDSDDDFY 2580 DTPLFEDDDH DSLLLDGDDR DCLHPEDYDT LQEENDETAS PADVFYDVSK ENENSMVPQG 2640 APVGSLSVKN KAHCLQDFLM DVEKDELDSG EKIHLNPVGS DKVNGQSLET GSERECTNIL 2700 EGDESDSLTD YDIVGGKESF TASLKFDDSG SWRGRKEEYV TGQEFHSDTD HLDSMQSEES 2760 YGDYIYDSND QDDDDDDGID EEGGGIRDEN GKPRCQNVAE DMDIQLCASI LNENSDENEN 2820 INTMILLDKM HSCSSLEKQQ RVNVVQLASP SENNLVTEKS NLPEYTTEIA GKSKENLLNH 2880 EMVLKDVLPP IIKDTESEKT FGPASISHDN NNISSTSELG TDLANTKVKL IQGSELPELT 2940 DSVKGKDEYF KNMTPKVDSS LDHIICTEPD LIGKPAEESH LSLIASVTDK DPQGNGSDLI 3000 KGRDGKSDIL IEDETSIQKM YLGEGEVLVE GLVEEENRHL KLLPGKNTRD SFKLINSQFP 3060 FPQITNNEEL NQKGSLKKAT VTLKDEPNNL QIIVSKSPVQ FENLEEIFDT SVSKEISDDI 3120 TSDITSWEGN THFEESFTDG PEKELDLFTY LKHCAKNIKA KDVAKPNEDV PSHVLITAPP 3180 MKEHLQLGVN NTKEKSTSTQ KDSPLNDMIQ SNDLCSKESI SGGGTEISQF TPESIEATLS 3240 ILSRKHVEDV GKNDFLQSER CANGLGNDNS SNTLNTDYSF LEINNKKERI EQQLPKEQAL 3300 SPRSQEKEVQ IPELSQVFVE DVKDILKSRL KEGHMNPQEV EEPSACADTK ILIQNLIKRI 3360 TTSQLVNEAS TVPSDSQMSD SSGVSPMTNS SELKPESRDD PFCIGNLKSE LLLNILKQDQ 3420 HSQKITGVFE LMRELTHMEY DLEKRGITSK VLPLQLENIF YKLLADGYSE KIEHVGDFNQ 3480 KACSTSEMME EKPHILGDIK SKEGNYYSPN LETVKEIGLE SSTVWASTLP RDEKLKDLCN 3540 DFPSHLECTS GSKEMASGDS STEQFSSELQ QCLQHTEKMH EYLTLLQDMK PPLDNQESLD 3600 NNLEALKNQL RQLETFELGL APIAVILRKD MKLAEEFLKS LPSDFPRGHV EELSISHQSL 3660 KTAFSSLSNV SSERTKQIML AIDSEMSKLA VSHEEFLHKL KSFSDWVSEK SKSVKDIEIV 3720 NVQDSEYVKK RLEFLKANNV LKDLGHTKMQ LETTAFDVQF FISEYAQDLS PNQSKQLLRL 3780 LNTTQKCFLD VQESVTTQVE RLETQLHLEQ DLDDQKIVAE RQQEYKEKLQ GICDLLTQTE 3840 NRLIGHQEAF MIGDGTVELK KYQSKQEELQ KDMQGSAQAL AEVVKNTENF LKENGEKLSQ 3900 EDKALIEQKL NEAKIKCEQL NLKAEQSKKE LDKVVTTAIK EETEKVAAVK QLEESKTKIE 3960 NLLDWLSNVD KDSERAGTKH KQVIEQNGTH FQEGDGKSAI GEEDEVNGNL LETDVDGQVG 4020 TTQENLNQQY QKVKAQHEKI ISQHQAVIIA TQSAQVLLEK QGQYLSPEEK EKLQKNMKEL 4080 KVHYETALAE SEKKMKLTHS LQEELEKFDA DYTEFEHWLQ QSEQELENLE AGADDINGLM 4140 TKLKRQKSFS EDVISHKGDL RYITISGNRV LEAAKSCSKR DGGKVDTSAT HREVQRKLDH 4200 ATDRFRSLYS KCNVLGNNLK DLVDKYQHYE DASCGLLAGL QACEATASKH LSEPIAVDPK 4260 NLQRQLEETK ALQGQISSQQ VAVEKLKKTA EVLLDARGSL LPAKNDIQKT LDDIVGRYED 4320 LSKSVNERNE KLQITLTRSL SVQDGLDEML DWMGNVESSL KEQGQVPLNS TALQDIISKN 4380 IMLEQDIAGR QSSINAMNEK VKKFMETTDP STASSLQAKM KDLSARFSEA SHKHKETLAK 4440 MEELKTKVEL FENLSEKLQT FLETKTQALT EVDVPGKDVT ELSQYMQEST SEFLEHKKHL 4500 EVLHSLLKEI SSHGLPSDKA LVLEKTNNLS KKFKEMEDTI KEKKEAVTSC QEQLDAFQVL 4560 VKSLKSWIKE TTKKVPIVQP SFGAEDLGKS LEDTKKLQEK WSLKTPEIQK VNNSGISLCN 4620 LISAVTTPAK AIAAVKSGGA VLNGEGTATN TEEFWANKGL TSIKKDMTDI SHGYEDLGLL 4680 LKDKIAELNT KLSKLQKAQE ESSAMMQWLQ KMNKTATKWQ QTPAPTDTEA VKTQVEQNKS 4740 FEAELKQNVN KVQELKDKLT ELLEENPDTP EAPRWKQMLT EIDSKWQELN QLTIDRQQKL 4800 EESSNNLTQF QTVEAQLKQW LVEKELMVSV LGPLSIDPNM LNTQRQQVQI LLQEFATRKP 4860 QYEQLTAAGQ GILSRPGEDP SLRGIVKEQL AAVTQKWDSL TGQLSDRCDW IDQAIVKSTQ 4920 YQSLLRSLSD KLSDLDNKLS SSLAVSTHPD AMNQQLETAQ KMKQEIQQEK KQIKVAQALC 4980 EDLSALVKEE YLKAELSRQL EGILKSFKDV EQKAENHVQH LQSACASSHQ FQQMSRDFQA 5040 WLDTKKEEQN KSHPISAKLD VLESLIKDHK DFSKTLTAQS HMYEKTIAEG ENLLLKTQGS 5100 EKAALQLQLN TIKTNWDTFN KQVKERENKL KESLEKALKY KEQVETLWPW IDKCQNNLEE 5160 IKFCLDPAEG ENSIAKLKSL QKEMDQHFGM VELLNNTANS LLSVCEIDKE VVTDENKSLI 5220 QKVDMVTEQL HSKKFCLENM TQKFKEFQEV SKESKRQLQC AKEQLDIHDS LGSQAYSNKY 5280 LTMLQTQQKS LQALKHQVDL AKRLAQDLVV EASDSKGTSD VLLQVETIAQ EHSTLSQQVD 5340 EKCSFLETKL QGIGHFQNTI REMFSQFAEF DDELDSMAPV GRDAETLQKQ KETIKAFLKK 5400 LEALMASNDN ANKTCKMMLA TEETSPDLVG IKRDLEALSK QCNKLLDRAQ AREEQVEGTI 5460 KRLEEFYSKL KEFSILLQKA EEHEESQGPV GMETETINQQ LNMFKVFQKE EIEPLQGKQQ 5520 DVNWLGQGLI QSAAKSTSTQ GLEHDLDDVN ARWKTLNKKV AQRAAQLQEA LLHCGRFQDA 5580 LESLLSWMVD TEELVANQKP PSAEFKVVKA QIQEQKLLQR LLDDRKSTVE VIKREGEKIA 5640 TTAEPADKVK ILKQLSLLDS RWEALLNKAE TRNRQLEGIS VVAQQFHETL EPLNEWLTTI 5700 EKRLVNCEPI GTQASKLEEQ IAQHKALEDD IINHNKHLHQ AVSIGQSLKV LSSREDKDMV 5760 QSKLDFSQVW YIEIQEKSHS RSELLQQALC NAKIFGEDEV ELMNWLNEVH DKLSKLSVQD 5820 YSTEGLWKQQ SELRVLQEDI LLRKQNVDQA LLNGLELLKQ TTGDEVLIIQ DKLEAIKARY 5880 KDITKLSTDV AKTLEQALQL ARRLHSTHEE LCTWLDKVEV ELLSYETQVL KGEEASQAQM 5940 RPKELKKEAK NNKALLDSLN EVSSALLELV PWRAREGLEK MVAEDNERYR LVSDTITQKV 6000 EEIDAAILRS QQFDQAADAE LSWITETEKK LMSLGDIRLE QDQTSAQLQV QKTFTMEILR 6060 HKDIIDDLVK SGHKIMTACS EEEKQSMKKK LDKVLKNYDT ICQINSERYL QLERAQSLVN 6120 QFWETYEELW PWLTETQSII SQLPAPALEY ETLRQQQEEH RQLRELIAEH KPHIDKMNKT 6180 GPQLLELSPG EGFSIQEKYV AADTLYSQIK EDVKKRAVAL DEAISQSTQF HDKIDQILES 6240 LERIVERLRQ PPSISAEVEK IKEQISENKN VSVDMEKLQP LYETLKQRGE EMIARSGGTD 6300 KDISAKAVQD KLDQMVFIWE NIHTLVEERE AKLLDVMELA EKFWCDHMSL IVTIKDTQDF 6360 IRDLEDPGID PSVVKQQQEA AETIREEIDG LQEELDIVIN LGSELIAACG EPDKPIVKKS 6420 IDELNSAWDS LNKAWKDRID KLEEAMQAAV QYQDGLQAVF DWVDIAGGKL ASMSPIGTDL 6480 ETVKQQIEEL KQFKSEAYQQ QIEMERLNHQ AELLLKKVTE ESDKHTVQDP LMELKLIWDS 6540 LEERIINRQH KLEGALLALG QFQHALDELL AWLTHTEGLL SEQKPVGGDP KAIEIELAKH 6600 HVLQNDVLAH QSTVEAVNKA GNDLIESSAG EEASNLQNKL EVLNQRWQNV LEKTEQRKQQ 6660 LDGALRQAKG FHGEIEDLQQ WLTDTERHLL ASKPLGGLPE TAKEQLNVHM EVCAAFEAKE 6720 ETYKSLMQKG QQMLARCPKS AETNIDQDIN NLKEKWESVE TKLNERKTKL EEALNLAMEF 6780 HNSLQDFINW LTQAEQTLNV ASRPSLILDT VLFQIDEHKV FANEVNSHRE QIIELDKTGT 6840 HLKYFSQKQD VVLIKNLLIS VQSRWEKVVQ RLVERGRSLD DARKRAKQFH EAWSKLMEWL 6900 EESEKSLDSE LEIANDPDKI KTQLAQHKEF QKSLGAKHSV YDTTNRTGRS LKEKTSLADD 6960 NLKLDDMLSE LRDKWDTICG KSVERQNKLE EALLFSGQFT DALQALIDWL YRVEPQLAED 7020 QPVHGDIDLV MNLIDNHKAF QKELGKRTSS VQALKRSARE LIEGSRDDSS WVKVQMQELS 7080 TRWETVCALS ISKQTRLEAA LRQAEEFHSV VHALLEWLAE AEQTLRFHGV LPDDEDALRT 7140 LIDQHKEFMK KLEEKRAELN KATTMGDTVL AICHPDSITT IKHWITIIRA RFEEVLAWAK 7200 QHQQRLASAL AGLIAKQELL EALLAWLQWA ETTLTDKDKE VIPQEIEEVK ALIAEHQTFM 7260 EEMTRKQPDV DKVTKTYKRR AADPSSLQSH IPVLDKGRAG RKRFPASSLY PSGSQTQIET 7320 KNPRVNLLVS KWQQVWLLAL ERRRKLNDAL DRLEELREFA NFDFDIWRKK YMRWMNHKKS 7380 RVMDFFRRID KDQDGKITRQ EFIDGILSSK FPTSRLEMSA VADIFDRDGD GYIDYYEFVA 7440 ALHPNKDAYK PITDADKIED EVTRQVAKCK CAKRFQVEQI GDNKYRVSFQ SNFGDSQQLR 7500 LVRILRSTVM VRVGGGWMAL DEFLVKNDPC RVHHHGSKML RSESNSSITT TQPTIAKGRT 7560 NMELREKFIL ADGASQGMAA FRPRGRRSRP SSRGASPNRS TSVSSQAAQA ASPQVPATTT 7620 PKGTPIQGSK LRLPGYLSGK GFHSGEDSGL ITTAAARVRT QFADSKKTPS RPGSRAGSKA 7680 GSRASSRRGS DASDFDISEI QSVCSDVETV PQTHRPTPRA GSRPSTAKPS KIPTPQRKSP 7740 ASKLDKSSKR 7750 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |