UniProt Accession

 H3BN42_HUMAN; H3BN42 

Genbank Protein ID

 AC024575 

Genbank Nucleotide ID

  

Protein Name

 Ral guanine nucleotide dissociation stimulator-like 3 

Protein Synonyms/Alias

  

Gene Name

 RGL3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
128	PPGVEIKKTAVQDLS	ubiquitination	[1]
138	VQDLSFNKNLRAVVS	ubiquitination	[1, 2]
186	PGSAEAQKAEKLLED	ubiquitination	[1, 2]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 250 AA 

Protein Sequence

Gene Ontology

 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
 GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 

Interpro

 IPR000651; Ras-like_Gua-exchang_fac_N.
 IPR008937; Ras_GEF.
 IPR023578; Ras_GEF_dom. 

Pfam

 PF00618; RasGEF_N 

SMART

 SM00229; RasGEFN 

PROSITE

 PS50212; RASGEF_NTER 

PRINTS