Tag | Content |
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CPLM ID | CPLM-020547 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Desumoylating isopeptidase 1 |
Protein Synonyms/Alias | DeSI-1; PPPDE peptidase domain-containing protein 2; Protein FAM152B |
Gene Name | Desi1 |
Gene Synonyms/Alias | D15Wsu75e; Fam152b; Pppde2 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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18 | LYVYDLSKGLARRLS | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity. Desumoylates ZBTB46. |
Sequence Annotation | DOMAIN 7 149 PPPDE peptidase. ACT_SITE 38 38 ACT_SITE 108 108 |
Keyword | 3D-structure; Complete proteome; Cytoplasm; Hydrolase; Nucleus; Protease; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 168 AA |
Protein Sequence | MEPPNLYPVK LYVYDLSKGL ARRLSPIMLG KQLEGIWHTS IVVHKDEFFF GSSGISSCTP 60 GGTLLGPPDS VVDVGNTEVT EEIFLEYLSS LGESLFRGEA YNLFEHNCNT FSNEVAQFLT 120 GRKIPSYITD LPSEVLSTPF GQALRPFLDS IQIQPPGGNS VGRPNGQS 168 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |