| Tag | Content |
|---|
| CPLM ID | CPLM-011591 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Alanine dehydrogenase |
Protein Synonyms/Alias | Stage V sporulation protein N |
Gene Name | ald |
Gene Synonyms/Alias | spoVN; BSU31930 |
Created Date | July 27, 2013 |
Organism | Bacillus subtilis (strain 168) |
NCBI Taxa ID | 224308 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 7 | *MIIGVPKEIKNNEN | acetylation | [1] | | 149 | IGAQFLEKPKGGKGI | acetylation | [1] |
|
Reference | [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis. Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG. Proteomics. 2013 May;13(10-11):1726-36. [ PMID: 23468065] |
Functional Description | Catalyzes the reversible oxidative deamination of L- alanine to pyruvate. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle during sporulation. |
Sequence Annotation | NP_BIND 176 177 NAD (By similarity).
NP_BIND 237 238 NAD (By similarity).
NP_BIND 265 268 NAD (By similarity).
NP_BIND 297 300 NAD (By similarity).
ACT_SITE 95 95 Proton donor/acceptor (By similarity).
ACT_SITE 268 268 Proton donor/acceptor (By similarity).
METAL 326 326 Magnesium; via tele nitrogen (By
BINDING 15 15 Substrate (By similarity).
BINDING 74 74 Substrate (By similarity).
BINDING 132 132 NAD (By similarity).
BINDING 196 196 NAD (By similarity).
BINDING 218 218 NAD (By similarity). |
Keyword | Complete proteome; Cytoplasm; Magnesium; Metal-binding; NAD; Nucleotide-binding; Oxidoreductase; Reference proteome; Sporulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 378 AA |
Protein Sequence | MIIGVPKEIK NNENRVALTP GGVSQLISNG HRVLVETGAG LGSGFENEAY ESAGAEIIAD 60
PKQVWDAEMV MKVKEPLPEE YVYFRKGLVL FTYLHLAAEP ELAQALKDKG VTAIAYETVS 120
EGRTLPLLTP MSEVAGRMAA QIGAQFLEKP KGGKGILLAG VPGVSRGKVT IIGGGVVGTN 180
AAKMAVGLGA DVTIIDLNAD RLRQLDDIFG HQIKTLISNP VNIADAVAEA DLLICAVLIP 240
GAKAPTLVTE EMVKQMKPGS VIVDVAIDQG GIVETVDHIT THDQPTYEKH GVVHYAVANM 300
PGAVPRTSTI ALTNVTVPYA LQIANKGAVK ALADNTALRA GLNTANGHVT YEAVARDLGY 360
EYVPAEKALQ DESSVAGA 378 |
Gene Ontology | GO:0005829; C:cytosol; ISS:UniProtKB. GO:0000286; F:alanine dehydrogenase activity; IMP:UniProtKB. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. GO:0006524; P:alanine catabolic process; ISS:UniProtKB. GO:0042853; P:L-alanine catabolic process; IEA:UniProtKB-UniPathway. GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |