CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002897
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Acetylglutamate kinase 
Protein Synonyms/Alias
 N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK 
Gene Name
 argB 
Gene Synonyms/Alias
 b3959; JW5553 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
53CVVDELMKGLNLPVKacetylation[1]
60KGLNLPVKKKNGLRVacetylation[1]
61GLNLPVKKKNGLRVTacetylation[1]
200IAEMTAAKAEQLIEQacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
  
Sequence Annotation
 NP_BIND 181 186 ATP.
 NP_BIND 209 211 ATP.
 REGION 44 45 Substrate binding.
 BINDING 66 66 Substrate.
 BINDING 158 158 Substrate.  
Keyword
 3D-structure; Amino-acid biosynthesis; Arginine biosynthesis; ATP-binding; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 258 AA 
Protein Sequence
MMNPLIIKLG GVLLDSEEAL ERLFSALVNY RESHQRPLVI VHGGGCVVDE LMKGLNLPVK 60
KKNGLRVTPA DQIDIITGAL AGTANKTLLA WAKKHQIAAV GLFLGDGDSV KVTQLDEELG 120
HVGLAQPGSP KLINSLLENG YLPVVSSIGV TDEGQLMNVN ADQAATALAA TLGADLILLS 180
DVSGILDGKG QRIAEMTAAK AEQLIEQGII TDGMIVKVNA ALDAARTLGR PVDIASWRHA 240
EQLPALFNGM PMGTRILA 258 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003991; F:acetylglutamate kinase activity; IDA:EcoCyc.
 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0006526; P:arginine biosynthetic process; IDA:EcoCyc.
 GO:0006974; P:response to DNA damage stimulus; IEP:EcoliWiki. 
Interpro
 IPR004662; AcgluKinase.
 IPR001048; Asp/Glu/Uridylate_kinase. 
Pfam
 PF00696; AA_kinase 
SMART
  
PROSITE
  
PRINTS