UniProt Accession

 H1BP3_HUMAN; Q53T59; B2RAW2; D6W529; Q86VC2; Q8N367 

Genbank Protein ID

 AK314383; AC012065; CH471053; CH471053; BC050636 

Genbank Nucleotide ID

 BAG37009.1; AAX93235.1; EAX00814.1; EAX00816.1; AAH50636.1 

Protein Name

 HCLS1-binding protein 3 

Protein Synonyms/Alias

 HS1-binding protein 3; HSP1BP-3 

Gene Name

 HS1BP3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
337	PKPPVAAKPVIPRKP	acetylation	[1, 2]

Reference

 [1] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861]
 [2] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773] 

Functional Description

 May be a modulator of IL-2 signaling (By similarity). 

Sequence Annotation

 DOMAIN 19 142 PX.
 MOD_RES 1 1 N-acetylmethionine.
 MOD_RES 3 3 Phosphoserine.
 MOD_RES 139 139 Phosphoserine.
 MOD_RES 194 194 Phosphoserine.
 MOD_RES 337 337 N6-acetyllysine.  

Keyword

 Acetylation; Complete proteome; Phosphoprotein; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 392 AA 

Protein Sequence

Gene Ontology

 GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
 GO:0007154; P:cell communication; IEA:InterPro. 

Interpro

 IPR001683; Phox. 

Pfam

 PF00787; PX 

SMART

 SM00312; PX 

PROSITE

 PS50195; PX 

PRINTS