UniProt Accession

 D3YZ18_MOUSE; D3YZ18 

Genbank Protein ID

 AC158782 

Genbank Nucleotide ID

  

Protein Name

 High mobility group protein B1 

Protein Synonyms/Alias

  

Gene Name

 Hmgb1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
88	PKGETKKKFKDPNAP	acetylation	[1]
90	GETKKKFKDPNAPKR	acetylation	[1]

Reference

 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 125 AA 

Protein Sequence

Gene Ontology

 GO:0009986; C:cell surface; IEA:Compara.
 GO:0000793; C:condensed chromosome; IEA:Compara.
 GO:0017053; C:transcriptional repressor complex; IEA:Compara.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Compara.
 GO:0006288; P:base-excision repair, DNA ligation; IEA:Compara.
 GO:0002437; P:inflammatory response to antigenic stimulus; IEA:Compara.
 GO:0017055; P:negative regulation of RNA polymerase II transcriptional preinitiation complex assembly; IEA:Compara.
 GO:0043065; P:positive regulation of apoptotic process; IEA:Compara.
 GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Compara.
 GO:0043388; P:positive regulation of DNA binding; IEA:Compara.
 GO:0033151; P:V(D)J recombination; IEA:Compara. 

Interpro

 IPR009071; HMG_box_dom.
 IPR017967; HMG_boxA_CS. 

Pfam

 PF09011; DUF1898
 PF00505; HMG_box 

SMART

 SM00398; HMG 

PROSITE

 PS00353; HMG_BOX_1
 PS50118; HMG_BOX_2 

PRINTS