| Tag | Content |
|---|
| CPLM ID | CPLM-006902 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Inner centromere protein-related protein SLI15 |
Protein Synonyms/Alias | INCENP-related protein SLI15 |
Gene Name | SLI15 |
Gene Synonyms/Alias | YBR156C; YBR1206 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 89 | DVEFPKMKGEYELSN | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Required for high-fidelity chromosome segregation during the later part of each cell cycle in association with the protein kinase IPL1. Stimulates IPL1 kinase activity and facilitates its association with the mitotic spindle. Has a role in attaching the kinetochores to the microtubules and ensuring that sister kinetochores connect to opposite poles. |
Sequence Annotation | MOD_RES 268 268 Phosphoserine.
MOD_RES 489 489 Phosphoserine. |
Keyword | Centromere; Chromosome; Chromosome partition; Complete proteome; Cytoplasm; Cytoskeleton; Kinetochore; Nucleus; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 698 AA |
Protein Sequence | MDWAIKAARK KTQRKPGSTR SIIETLDDLN NLTTDAHSEI NQRLYESSEW LRNNVYMNTL 60
KYEDKKMEES LISPENTHNK MDVEFPKMKG EYELSNSQND AAKDVTKTPR NGLHNDKSIT 120
PKSLRRKEVT EGMNRFSIHD TNKSPVEPLN SVKVDANESE KSSPWSPYKV EKVLRESSKT 180
SESPINTKRF DNQTWAAKEE MENEPILQAL KKAESVKVKP PPNSGIARSQ RRSNMFVPLP 240
NKDPLIIQHI PPTKSSGSIP KVRTVKESPI AFKKKSTINS PAIRAVENSD TAGSTKASSV 300
FDRLSSIPTK SFENKISRGN VGHKYSSSSI DLTGSPMKKV SQKFKSINST DTDMQEALRD 360
IFSVKNKITK NNSPKGKNSR KSSIPRFDKT SLKLTTHKKL AIIAEQKKKS KHSSDVHKTG 420
SRPHSISPTK ISVDSSSPSK EVKNYYQSPV RGYLRPTKAS ISPNKNKNLT TSQTPHRLKI 480
KEKTLRKLSP NIADISKPES RKSKNYRLTN LQLLPPAEAE RDDLKKKFDK RLSGIMRSQQ 540
EHHRRKQEKQ KRMSHLEQDL KKQTSFSNDY KDIRLKESLA PFDNHVRDTI NKNTAFSTDN 600
ILATINTVDH REIIGNVTPK IASVNDSLPE INTDSEDEAS VTLAAWAKSP YLQEQLIRQQ 660
DINPQTIFGP IPPLHTDEIF PNPRLNRLKP RQIVPKRS 698 |
Gene Ontology | GO:0032133; C:chromosome passenger complex; IDA:SGD. GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell. GO:0005737; C:cytoplasm; IEA:UniProtKB-KW. GO:0005828; C:kinetochore microtubule; IDA:SGD. GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0051233; C:spindle midzone; IDA:SGD. GO:0030295; F:protein kinase activator activity; IMP:SGD. GO:0007059; P:chromosome segregation; TAS:SGD. GO:0006468; P:protein phosphorylation; IDA:SGD. GO:0032465; P:regulation of cytokinesis; IMP:SGD. |
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Pfam | |
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PRINTS | |