CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002732
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Valine--pyruvate aminotransferase 
Protein Synonyms/Alias
 Alanine--valine transaminase; Transaminase C 
Gene Name
 avtA 
Gene Synonyms/Alias
 b3572; JW5652 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
307RLSETVIKPFYYQRVacetylation[1]
353KDLPITTKQLYQRLKacetylation[1]
378NFFPGLDKPWPHTHQacetylation[1]
397NYVPEPEKIEAGVKIacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Involved in the biosynthesis of alanine. 
Sequence Annotation
 MOD_RES 249 249 N6-(pyridoxal phosphate)lysine (By  
Keyword
 Aminotransferase; Complete proteome; Cytoplasm; Pyridoxal phosphate; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 417 AA 
Protein Sequence
MTFSLFGDKF TRHSGITLLM EDLNDGLRTP GAIMLGGGNP AQIPEMQDYF QTLLTDMLES 60
GKATDALCNY DGPQGKTELL TLLAGMLREK LGWDIEPQNI ALTNGSQSAF FYLFNLFAGR 120
RADGRVKKVL FPLAPEYIGY ADAGLEEDLF VSARPNIELL PEGQFKYHVD FEHLHIGEET 180
GMICVSRPTN PTGNVITDEE LLKLDALANQ HGIPLVIDNA YGVPFPGIIF SEARPLWNPN 240
IVLCMSLSKL GLPGSRCGII IANEKIITAI TNMNGIISLA PGGIGPAMMC EMIKRNDLLR 300
LSETVIKPFY YQRVQETIAI IRRYLPENRC LIHKPEGAIF LWLWFKDLPI TTKQLYQRLK 360
ARGVLMVPGH NFFPGLDKPW PHTHQCMRMN YVPEPEKIEA GVKILAEEIE RAWAESH 417 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0009042; F:valine-pyruvate transaminase activity; IDA:EcoCyc.
 GO:0009063; P:cellular amino acid catabolic process; EXP:EcoCyc.
 GO:0030632; P:D-alanine biosynthetic process; IMP:UniProtKB.
 GO:0006090; P:pyruvate metabolic process; EXP:EcoCyc.
 GO:0009099; P:valine biosynthetic process; EXP:EcoCyc. 
Interpro
 IPR004839; Aminotransferase_I/II.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1.
 IPR015422; PyrdxlP-dep_Trfase_major_sub2. 
Pfam
 PF00155; Aminotran_1_2 
SMART
  
PROSITE
  
PRINTS