CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032178
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein NADK2 
Protein Synonyms/Alias
 cDNA FLJ55867 
Gene Name
 NADK2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
7*MLLAASKVLDRLKPubiquitination[1]
176LCTGTGSKAWSFNINubiquitination[1]
198EDVLNIAKRQGNLSLubiquitination[1, 2, 3, 4]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 301 AA 
Protein Sequence
MLLAASKVLD RLKPVIGVNT DPERSEGHLC LPVRYTHSFP EALQKFYRGE FRWLWRQRIR 60
LYLEGTGINP VPVDLHEQQL SLNQHNRALN IERAHDERSE ASGPQLLPVR ALNEVFIGES 120
LSSRMSYSWA VAVDNLRRSI PTLKGLASYY EISVDDGPWE KQKSSGLNLC TGTGSKAWSF 180
NINRVATQAV EDVLNIAKRQ GNLSLPLNRE LVEKVTNEYN ESLLYSPEEP KILFSIREPI 240
ANRVFSSSRQ RCFSSKVCVR SRCWDACMVV DGGTSFEFND GAIASMMINK EDELRTVLLE 300
Q 301 
Gene Ontology
 GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
 GO:0019674; P:NAD metabolic process; IEA:InterPro. 
Interpro
 IPR012355; ATP-NAD-like_euk.
 IPR017438; ATP-NAD_kinase_dom_1.
 IPR016064; ATP-NAD_kinase_PpnK-typ.
 IPR017437; ATP-NAD_kinase_PpnK-typ_all-b. 
Pfam
  
SMART
  
PROSITE
  
PRINTS