UniProt Accession

 C9JRL4_HUMAN; C9JRL4 

Genbank Protein ID

 AC016734 

Genbank Nucleotide ID

  

Protein Name

 Malate dehydrogenase, cytoplasmic 

Protein Synonyms/Alias

  

Gene Name

 MDH1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
80	KYAKKSVKVIVVGNP	ubiquitination	[1]
104	KSAPSIPKENFSCLT	ubiquitination	[1]

Reference

 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 120 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0030060; F:L-malate dehydrogenase activity; IEA:Compara.
 GO:0051287; F:NAD binding; IEA:Compara.
 GO:0006108; P:malate metabolic process; IEA:Compara.
 GO:0006734; P:NADH metabolic process; IEA:Compara.
 GO:0006107; P:oxaloacetate metabolic process; IEA:Compara. 

Interpro

 IPR001236; Lactate/malate_DH_N.
 IPR010945; Malate_DH_type2.
 IPR016040; NAD(P)-bd_dom. 

Pfam

 PF00056; Ldh_1_N 

SMART

  

PROSITE

  

PRINTS