| Tag | Content |
|---|
| CPLM ID | CPLM-028099 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Lysine ketoglutarate reductase |
Protein Synonyms/Alias | |
Gene Name | LKR |
Gene Synonyms/Alias | CG7144; Dmel_CG7144 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 47 | FGPTHVQKLVKQNVK | acetylation | [1] | | 427 | PHVHDIIKSDAKKPL | acetylation | [1] | | 711 | FPNRDSTKYGNLYGL | acetylation | [1] |
|
Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | |
Sequence Annotation | |
Keyword | Complete proteome; Oxidoreductase; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 928 AA |
Protein Sequence | MWRVIQLRAT IAHPFTRQRH SRVIAIRRED QSVWERRAPF GPTHVQKLVK QNVKVIVQPS 60
NRRAYPMQAY MQAGAHIQED ISDASVIFGV KQVPIDALIP GKTYCFFSHT IKAQESNMPL 120
LDAILEKKIR LIDYERIIDE RGARQVAFGK YAGVAGMVNI LHGIGLRLLA LGHHTPFMHI 180
GPAHNYRNSS MARQAIRDCG YEISLGMMPK SIGPLTFVFT GSGNVSQGAQ EVFSELPIEY 240
VPPEMLRKVA EHGNQNKLYG CEVSRSDHLE RREGGGFDAK EYDEFPERYI STFSTKIAPY 300
ASVIVNGIYW AVGSPKLISI PDAKNLLRPA NTPWLPTSKG SPALPHRMLA ICDISADPGG 360
SIEFMNECTT IDTPFCLYDA DRNKDTKSFK GPGVLVCSID NMPTQLPRES TDLFGELLAP 420
HVHDIIKSDA KKPLAEENFS YPIQSAIIAS NGQLTEGFQY IQELRESQSH RSRHKMEGSS 480
ESDKKVLVLG AGMVSAPLVE WLHREKDVSI TVCSQVKEEA DRLAQQYAGV DSVYLDVNES 540
TGHLQELCGR ADVVVSLLPY SLHGMVARYC VAEGTHMVTA SYLNDEISGL HEEAKAKGVT 600
IMNEVGLDPG IDHLLALECI HEVQDKGAVV ESFVSYCGGL PAPEHSNNAL RYKFSWSPRG 660
VLLNTLSAAK YLSQGQIVEI SGGGELMSSP RSLDFLPGFA LEGFPNRDST KYGNLYGLGR 720
DVHTLLRGTI RYKGFSESIK PMQLLGLIDP EPHALLHPSG PDVTWRQLVI HLMGMSDSTI 780
FYENLKQKLT ERIGDVDGIE SLGLLDDTPV VKLNTPLDTL SHYLSKRLAF ERDERDLVVL 840
RHEVGIRWPD GRREERGINF VVYGQPQGHS AMAMTVGKPA AIAAKMILDG EIQERGVLLP 900
FTPDIYRPML QRLRSEGLTA TETSRWLN 928 |
Gene Ontology | GO:0004754; F:saccharopine dehydrogenase (NAD+, L-lysine-forming) activity; IEA:EC. GO:0034969; P:histone arginine methylation; IDA:FlyBase. GO:0031060; P:regulation of histone methylation; IDA:FlyBase. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |