CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027279
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Pcdh1 
Protein Synonyms/Alias
 Protocadherin 1 
Gene Name
 Pcdh1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1010NPPKYPSKQVGQPFRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Calcium; Cell adhesion; Complete proteome; Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1038 AA 
Protein Sequence
MGPLRPSPGP GGQRLLLPPL LLALLLLLAP SASHTTQVVY KVPEEQPPNT LIGSLAADYG 60
LPDVGHLYKL EVGAPYLRVD GKTGDIFTTE TSIDREGLRE CQNQIPGNPC ILEFEVSITD 120
LVQNGSPRLL EGQIEVQDIN DNTPNFASPV ITLAIPENTN IGSLFPIPLA TDRDAGPNGV 180
ASYELQAGPE AQELFGLQVA EDQEEKQPQL IVMGNLDRER WDSYDLTIKV QDGGNPPRAS 240
SALLRVTVLD TNDNAPKFER PTYEAELSEN SPIGHSVIQV KANDSDQGAN AEIDYTFHQA 300
PEVVRRLLRL DRNTGLITVQ GPVDREDLST LRFSVLAKDR GATPKSARAQ VVVTVKDMND 360
NAPTIEIRGI GLVTHQDGMA NISEDVAEET AVALVQVSDR DEGENAAVTC VVAGDVPFQL 420
RQASETGSDS KKKYFLQTTT PLDYEKVKDY TIEIVAVDSG NPPLSSTNSL KVQVVDVNDN 480
APVFTQSITE VAFPENNKPG EVVAEVTASD ADSGSNAELV YSLEPEPAAQ GLFTISPENG 540
EIRVKTSLDR EQRDSYELKV VAADRGSPSL QGTATVLVNV LDCNDNDPKF MLSGYNFSVM 600
ENMPALSPVG MVTVIDGDKG ENARVQLSVE QDNGDFVIQN GTGTILSSLS FDREQQSTYT 660
FQLKAVDGGV PPRSAYVGVT INVLDENDNA PFITAPSNTS HRLLTPQTRL GETVSQVTAE 720
DIDSGINAEL TYSIAGGNPY GLFQIGSHSG AITLEKEIER RHHGLHRLVV KVSDRGKPPR 780
YGTALVHLYV NETLANRTLL ETLLVHSLDT PLDIDIAGDP EYERSKQRGN ILFGVVAGVV 840
AVALLIALAV LVRYCRQREA KSGYQAGKKE TKDLYAPKPS GKAAKGSKSK GKKSKSPKPV 900
KPVEDEDDTG LQKSLKFNLM SDAPGDSPRI HLPLNYPPGS PDLGRHYRSN SPLPSIQLQP 960
QSPSASKKHQ VVQDLPPANT FVGTGDTTST GSEQYSDYSY RTNPPKYPSK QVGQPFRLST 1020
PQPPPHPYHG AIWTEVWE 1038 
Gene Ontology
 GO:0005911; C:cell-cell junction; TAS:MGI.
 GO:0005887; C:integral to plasma membrane; TAS:MGI.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0016339; P:calcium-dependent cell-cell adhesion; TAS:MGI.
 GO:0007156; P:homophilic cell adhesion; TAS:MGI. 
Interpro
 IPR002126; Cadherin.
 IPR015919; Cadherin-like.
 IPR020894; Cadherin_CS.
 IPR013164; Cadherin_N.
 IPR013585; Protocadherin. 
Pfam
 PF00028; Cadherin
 PF08266; Cadherin_2
 PF08374; Protocadherin 
SMART
 SM00112; CA 
PROSITE
 PS00232; CADHERIN_1
 PS50268; CADHERIN_2 
PRINTS
 PR00205; CADHERIN.