CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021635
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glyoxalase domain-containing protein 4 
Protein Synonyms/Alias
  
Gene Name
 GLOD4 
Gene Synonyms/Alias
 C17orf25; CGI-150; My027 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
30YRDVLGMKVESCSVAubiquitination[1]
224IAFSCPQKELPDLEDubiquitination[1]
305KSDEWFAKHNKPKASacetylation[2]
308EWFAKHNKPKASG**acetylation[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861
Functional Description
  
Sequence Annotation
  
Keyword
 3D-structure; Alternative splicing; Complete proteome; Direct protein sequencing; Mitochondrion; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 313 AA 
Protein Sequence
MAARRALHFV FKVGNRFQTA RFYRDVLGMK VESCSVARLE CSGAISAHCS DYTRITEDSF 60
SKPYDGKWSK TMVGFGPEDD HFVAELTYNY GVGDYKLGND FMGITLASSQ AVSNARKLEW 120
PLTEVAEGVF ETEAPGGYKF YLQNRSLPQS DPVLKVTLAV SDLQKSLNYW CNLLGMKIYE 180
KDEEKQRALL GYADNQCKLE LQGVKGGVDH AAAFGRIAFS CPQKELPDLE DLMKRENQKI 240
LTPLVSLDTP GKATVQVVIL ADPDGHEICF VGDEAFRELS KMDPEGSKLL DDAMAADKSD 300
EWFAKHNKPK ASG 313 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. 
Interpro
 IPR025870; Glyoxalase-like_dom. 
Pfam
 PF12681; Glyoxalase_2 
SMART
  
PROSITE
  
PRINTS