CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010238
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable L,D-transpeptidase YnhG 
Protein Synonyms/Alias
  
Gene Name
 ynhG 
Gene Synonyms/Alias
 b1678; JW1668 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
49YTVQEGDKNLQAIARacetylation[1]
218RMNAPDIKALFSSVRacetylation[1]
278PAGFTQFKDNKAVDQacetylation[1]
286DNKAVDQKLVDKALYacetylation[1]
290VDQKLVDKALYRRAGacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Responsible, at least in part, for generating a meso- diaminopimelyl-3-a meso-diaminopimelyl-3 cross-link. 
Sequence Annotation
 REPEAT 42 85 LysM.
 ACT_SITE 209 209 Potential.  
Keyword
 Cell shape; Cell wall biogenesis/degradation; Complete proteome; Glycosyltransferase; Hydrolase; Peptidoglycan synthesis; Periplasm; Reference proteome; Signal; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 334 AA 
Protein Sequence
MKRASLLTLT LIGAFSAIQA AWAVDYPLPP TGSRLVGQNQ TYTVQEGDKN LQAIARRFDT 60
AAMLILEANN TIAPVPKPGT TITIPSQLLL PDAPRQGIIV NLAELRLYYY PPGENIVQVY 120
PIGIGLQGLE TPVMETRVGQ KIPNPTWTPT AGIRQRSLER GIKLPPVVPA GPNNPLGRYA 180
LRLAHGNGEY LIHGTSAPDS VGLRVSSGCI RMNAPDIKAL FSSVRTGTPV KVINEPVKYS 240
VEPNGMRYVE VHRPLSAEEQ QNVQTMPYTL PAGFTQFKDN KAVDQKLVDK ALYRRAGYPV 300
SVSSGATPAA SNAPSVESAQ NGEPEQGNML RVTQ 334 
Gene Ontology
 GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
 GO:0016807; F:cysteine-type carboxypeptidase activity; IMP:EcoCyc.
 GO:0071972; F:peptidoglycan L,D-transpeptidase activity; IMP:EcoCyc.
 GO:0016755; F:transferase activity, transferring amino-acyl groups; IMP:EcoCyc.
 GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
 GO:0016998; P:cell wall macromolecule catabolic process; IEA:InterPro.
 GO:0044036; P:cell wall macromolecule metabolic process; IMP:EcoCyc.
 GO:0043164; P:Gram-negative-bacterium-type cell wall biogenesis; IMP:EcoCyc.
 GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-UniPathway.
 GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW. 
Interpro
 IPR005490; LD_TPept_cat_dom.
 IPR018392; Peptidoglycan-bd_lysin.
 IPR002482; Peptidoglycan-bd_Lysin_subgr. 
Pfam
 PF01476; LysM
 PF03734; YkuD 
SMART
 SM00257; LysM 
PROSITE
  
PRINTS