CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007615
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable electron transfer flavoprotein subunit beta 
Protein Synonyms/Alias
 Beta-ETF; Changed intracellular redox state protein 1 
Gene Name
 CIR1 
Gene Synonyms/Alias
 YGR207C; G7742 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
75AVSIGSAKAQDILRNacetylation[1]
217IEKLDIAKDFPEINIacetylation[1]
254SVDELIEKLKEVKAIacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl- CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Electron transport; FAD; Flavoprotein; Mitochondrion; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 261 AA 
Protein Sequence
MSAKQQLRIL VPVKRVVDFQ IKPRVNKTLT GIETSGIKFS INPFDDIAVE EAIRIKEKNK 60
SLVESTHAVS IGSAKAQDIL RNCLAKGIDT CSLIDSVGKE NIEPLAIAKI LKAVVEKKGS 120
NLVLMGKQAI DDDCNNTGQM LAGLLNWPQA TNAAKVEFLD NGRVQVTREI DDGEEVIEAS 180
LPMVITTDLR LNTPRYVGLP KLMKAKKKPI EKLDIAKDFP EINIEPQLKI VSMEEPKTKS 240
PGVKLNSVDE LIEKLKEVKA I 261 
Gene Ontology
 GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0022900; P:electron transport chain; IEA:UniProtKB-KW. 
Interpro
 IPR000049; ET-Flavoprotein_bsu_CS.
 IPR014730; ETF_a/b_N.
 IPR012255; ETF_b.
 IPR014729; Rossmann-like_a/b/a_fold. 
Pfam
 PF01012; ETF 
SMART
 SM00893; ETF 
PROSITE
 PS01065; ETF_BETA 
PRINTS