UniProt Accession

 ADHC_MYCTU; P0A4X0; L0TE62; P31975 

Genbank Protein ID

 AE000516; AL123456 

Genbank Nucleotide ID

 AAK47460.1; CCP45854.1 

Protein Name

 NADP-dependent alcohol dehydrogenase C 

Protein Synonyms/Alias

  

Gene Name

 adhC 

Gene Synonyms/Alias

 adh; Rv3045; MT3130; MTV012.60 

Created Date

 July 27, 2013 

Organism

 Mycobacterium tuberculosis 

NCBI Taxa ID

 1773 

Lysine Modification

Position	Peptide	Type	References
209	TVLSQSLKKMEDGLR	pupylation	[1]

Reference

 [1] Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected] .
 Festa RA, McAllister F, Pearce MJ, Mintseris J, Burns KE, Gygi SP, Darwin KH.
 PLoS One. 2010 Jan 6;5(1):e8589. [PMID: 20066036] 

Functional Description

  

Sequence Annotation

 METAL 41 41 Zinc 1; catalytic (By similarity).
 METAL 63 63 Zinc 1; catalytic (By similarity).
 METAL 94 94 Zinc 2 (By similarity).
 METAL 97 97 Zinc 2 (By similarity).
 METAL 100 100 Zinc 2 (By similarity).
 METAL 108 108 Zinc 2 (By similarity).
 METAL 158 158 Zinc 1; catalytic (By similarity).
 CROSSLNK 209 209 Isoglutamyl lysine isopeptide (Lys-Gln)  

Keyword

 Complete proteome; Isopeptide bond; Metal-binding; NADP; Oxidoreductase; Reference proteome; Ubl conjugation; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 346 AA 

Protein Sequence

Gene Ontology

 GO:0005618; C:cell wall; IDA:MTBBASE.
 GO:0005829; C:cytosol; IDA:MTBBASE.
 GO:0005886; C:plasma membrane; IDA:MTBBASE.
 GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 

Interpro

 IPR013149; ADH_C.
 IPR013154; ADH_GroES-like.
 IPR002085; ADH_SF_Zn-type.
 IPR002328; ADH_Zn_CS.
 IPR011032; GroES-like.
 IPR016040; NAD(P)-bd_dom. 

Pfam

 PF08240; ADH_N
 PF00107; ADH_zinc_N 

SMART

  

PROSITE

 PS00059; ADH_ZINC 

PRINTS