| Tag | Content |
|---|
| CPLM ID | CPLM-014994 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Keratin, type II cytoskeletal 80 |
Protein Synonyms/Alias | Cytokeratin-80; CK-80; Keratin-80; K80; Type-II keratin Kb20 |
Gene Name | KRT80 |
Gene Synonyms/Alias | KB20 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 71 | LLVPLDVKLDPAVQQ | ubiquitination | [1] | | 93 | EMKALNDKFASLIGK | ubiquitination | [1] | | 100 | KFASLIGKVQALEQR | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | |
Sequence Annotation | REGION 1 82 Head.
REGION 82 118 Coil 1A.
REGION 83 390 Rod.
REGION 119 135 Linker 1.
REGION 136 227 Coil 1B.
REGION 228 251 Linker 12.
REGION 252 390 Coil 2.
REGION 391 452 Tail.
MOD_RES 45 45 Phosphoserine.
MOD_RES 396 396 Phosphoserine. |
Keyword | Alternative splicing; Coiled coil; Complete proteome; Intermediate filament; Keratin; Phosphoprotein; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 452 AA |
Protein Sequence | MACRSCVVGF SSLSSCEVTP VGSPRPGTSG WDSCRAPGPG FSSRSLTGCW SAGTISKVTV 60
NPGLLVPLDV KLDPAVQQLK NQEKEEMKAL NDKFASLIGK VQALEQRNQL LETRWSFLQG 120
QDSAIFDLGH LYEEYQGRLQ EELRKVSQER GQLEANLLQV LEKVEEFRIR YEDEISKRTD 180
MEFTFVQLKK DLDAECLHRT ELETKLKSLE SFVELMKTIY EQELKDLAAQ VKDVSVTVGM 240
DSRCHIDLSG IVEEVKAQYD AVAARSLEEA EAYSRSQLEE QAARSAEYGS SLQSSRSEIA 300
DLNVRIQKLR SQILSVKSHC LKLEENIKTA EEQGELAFQD AKTKLAQLEA ALQQAKQDMA 360
RQLRKYQELM NVKLALDIEI ATYRKLVEGE EGRMDSPSAT VVSAVQSRCK TAPSLPYPLC 420
SL 422 |
Gene Ontology | GO:0045095; C:keratin filament; IEA:InterPro. GO:0005198; F:structural molecule activity; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |