CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041888
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Laminin subunit beta-1 
Protein Synonyms/Alias
 Laminin, beta 1, isoform CRA_a 
Gene Name
 LAMB1 
Gene Synonyms/Alias
 hCG_17112 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
1268SPAAEPLKNIGNLFEubiquitination[1]
1334AEQLEFIKNSDIRGAubiquitination[2]
1731KVENLIAKKTEESADubiquitination[3]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Disulfide bond; Laminin EGF-like domain; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1810 AA 
Protein Sequence
MDCPLSAPTP PPPLVRFFRA PLPACVPPTL LPVLPAALCR ARVRAQEPEF SYGCAEGSCY 60
PATGDLLIGR AQKLSVTSTC GLHKPEPYCI VSHLQEDKKC FICNSQDPYH ETLNPDSHLI 120
ENVVTTFAPN RLKIWWQSEN GVENVTIQLD LEAEFHFTHL IMTFKTFRPA AMLIERSSDF 180
GKTWGVYRYF AYDCEASFPG ISTGPMKKVD DIICDSRYSD IEPSTEGEVI FRALDPAFKI 240
EDPYSPRIQN LLKITNLRIK FVKLHTLGDN LLDSRMEIRE KYYYAVYDMV VRGNCFCYGH 300
ASECAPVDGF NEEVEGMVHG HCMCRHNTKG LNCELCMDFY HDLPWRPAEG RNSNACKKCN 360
CNEHSISCHF DMAVYLATGN VSGGVCDDCQ HNTMGRNCEQ CKPFYYQHPE RDIRDPNFCE 420
RCTCDPAGSQ NEGICDSYTD FSTGLIAGQC RCKLNVEGEH CDVCKEGFYD LSSEDPFGCK 480
SCACNPLGTI PGGNPCDSET GHCYCKRLVT GQHCDQCLPE HWGLSNDLDG CRPCDCDLGG 540
ALNNSCFAES GQCSCRPHMI GRQCNEVEPG YYFATLDHYL YEAEEANLGP GVSIVERQYI 600
QDRIPSWTGA GFVRVPEGAY LEFFIDNIPY SMEYDILIRY EPQLPDHWEK AVITVQRPGR 660
IPTSSRCGNT IPDDDNQVVS LSPGSRYVVL PRPVCFEKGT NYTVRLELPQ YTSSDSDVES 720
PYTLIDSLVL MPYCKSLDIF TVGGSGDGVV TNSAWETFQR YRCLENSRSV VKTPMTDVCR 780
NIIFSISALL HQTGLACECD PQGSLSSVCD PNGGQCQCRP NVVGRTCNRC APGTFGFGPS 840
GCKPCECHLQ GSVNAFCNPV TGQCHCFQGV YARQCDRCLP GHWGFPSCQP CQCNGHADDC 900
DPVTGECLNC QDYTMGHNCE RCLAGYYGDP IIGSGDHCRP CPCPDGPDSG RQFARSCYQD 960
PVTLQLACVC DPGYIGSRCD DCASGYFGNP SEVGGSCQPC QCHNNIDTTD PEACDKETGR 1020
CLKCLYHTEG EHCQFCRFGY YGDALQQDCR KCVCNYLGTV QEHCNGSDCQ CDKATGQCLC 1080
LPNVIGQNCD RCAPNTWQLA SGTGCDPCNC NAAHSFGPSC NEFTGQCQCM PGFGGRTCSE 1140
CQELFWGDPD VECRACDCDP RGIETPQCDQ STGQCVCVEG VEGPRCDKCT RGYSGVFPDC 1200
TPCHQCFALW DVIIAELTNR THRFLEKAKA LKISGVIGPY RETVDSVERK VSEIKDILAQ 1260
SPAAEPLKNI GNLFEEAEKL IKDVTEMMAQ VEVKLSDTTS QSNSTAKELD SLQTEAESLD 1320
NTVKELAEQL EFIKNSDIRG ALDSITKYFQ MSLEAEERVN ASTTEPNSTV EQSALMRDRV 1380
EDVMMERESQ FKEKQEEQAR LLDELAGKLQ SLDLSAAAEM TCGTPPGASC SETECGGPNC 1440
RTDEGERKCG GPGCGGLVTV AHNAWQKAMD LDQDVLSALA EVEQLSKMVS EAKLRADEAK 1500
QSAEDILLKT NATKEKMDKS NEELRNLIKQ IRNFLTQDSA DLDSIEAVAN EVLKMEMPST 1560
PQQLQNLTED IRERVESLSQ VEVILQHSAA DIARAEMLLE EAKRASKSAT DVKVTADMVK 1620
EALEEAEKAQ VAAEKAIKQA DEDIQGTQNL LTSIESETAA SEETLFNASQ RISELERNVE 1680
ELKRKAAQNS GEAEYIEKVV YTVKQSAEDV KKTLDGELDE KYKKVENLIA KKTEESADAR 1740
RKAEMLQNEA KTLLAQANSK LQLLKDLERK YEDNQRYLED KAQELARLEG EVRSLLKDIS 1800
QKVAVYSTCL 1810 
Gene Ontology
  
Interpro
 IPR002049; EGF_laminin.
 IPR013015; Laminin_IV.
 IPR008211; Laminin_N.
 IPR009053; Prefoldin. 
Pfam
 PF00053; Laminin_EGF
 PF00055; Laminin_N 
SMART
 SM00180; EGF_Lam
 SM00136; LamNT 
PROSITE
 PS01248; EGF_LAM_1
 PS50027; EGF_LAM_2
 PS51116; LAMININ_IVB
 PS51117; LAMININ_NTER 
PRINTS