| Tag | Content |
|---|
| CPLM ID | CPLM-019920 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | V-type proton ATPase subunit C 2 |
Protein Synonyms/Alias | V-ATPase subunit C 2; Vacuolar proton pump subunit C 2 |
Gene Name | Atp6v1c2 |
Gene Synonyms/Alias | Atp6c2 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 13 | LISAPGDKENLQALE | ubiquitination | [1] | | 124 | DMAKYPAKQPLVSVV | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. |
Sequence Annotation | |
Keyword | Alternative splicing; Complete proteome; Hydrogen ion transport; Ion transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 427 AA |
Protein Sequence | MSEFWLISAP GDKENLQALE RMNNVTSKSN LSHNTKFAIP DFKVGTLDSL VGLSDELGKL 60
DTFAESLIKR MAQSVVEVME DSKGKAHETL LANGGLKEKM KCLKIDLTSF VTHFEWDMAK 120
YPAKQPLVSV VDTLAKQLAQ IETDLKSRTA AYSVLKANLE NLEKRSTGNL FTRTLSDIVS 180
KEDFVLDSEY LITLLVIVPK SSFAQWQKTY ESLSDMVVPR STKLIAEDNE GGLFTVTLFR 240
KVIEDFKVKA KENKFIVREF YYDEKEIKRE REEMTRLLSD KKQQYPTSCV ALKKGSATYR 300
DHKVKVAPLG NPARPAAGQT DRDRESEGEG EGPLLRWLKV NFSEAFIAWI HIKALRVFVE 360
SVLRYGLPVN FQAVLLQPHK KSATKRLREV LNSVFRHLDE VAAASILDAS VEIPGLQLSN 420
QDYFPYVYFH IDLSLLD 437 |
Gene Ontology | GO:0033180; C:proton-transporting V-type ATPase, V1 domain; IEA:InterPro. GO:0008553; F:hydrogen-exporting ATPase activity, phosphorylative mechanism; IDA:MGI. GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |