CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042066
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Superoxide dismutase 
Protein Synonyms/Alias
  
Gene Name
 Sod2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Cavia porcellus (Guinea pig) 
NCBI Taxa ID
 10141 
Lysine Modification
Position
Peptide
Type
References
61NLNIAEEKYQEALAKacetylation[1]
68KYQEALAKGDVTAQVacetylation[1]
115GELLEAIKRDFGSFDacetylation[1]
123RDFGSFDKFKEKLTAacetylation[1]
125FGSFDKFKEKLTAVSacetylation[1]
Reference
 [1] The cardiac acetyl-lysine proteome.
 Foster DB, Liu T, Rucker J, O'Meally RN, Devine LR, Cole RN, O'Rourke B.
 PLoS One. 2013;8(7):e67513. [PMID: 23844019
Functional Description
 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 204 AA 
Protein Sequence
SASRRLAPAL GILGVRQKHS LPDLPYDYGA LQPHINAEIM QLHHSKHHAA YVNNLNIAEE 60
KYQEALAKGD VTAQVALQPA LKFNGGGHIN HSIFWTNLSP NGGGEPKGEL LEAIKRDFGS 120
FDKFKEKLTA VSVGVQGSGW GWLGFNKERG CLQIAACSNQ DPLQGTTGLI PLLGIDVWEH 180
AYYLQYKNVR PDYLKAIWNV INWE 204 
Gene Ontology
 GO:0005743; C:mitochondrial inner membrane; IEA:Compara.
 GO:0046872; F:metal ion binding; IEA:InterPro.
 GO:0004784; F:superoxide dismutase activity; IEA:EC.
 GO:0001315; P:age-dependent response to reactive oxygen species; IEA:Compara.
 GO:0003032; P:detection of oxygen; IEA:Compara.
 GO:0048773; P:erythrophore differentiation; IEA:Compara.
 GO:0006749; P:glutathione metabolic process; IEA:Compara.
 GO:0007507; P:heart development; IEA:Compara.
 GO:0030097; P:hemopoiesis; IEA:Compara.
 GO:0055072; P:iron ion homeostasis; IEA:Compara.
 GO:0001889; P:liver development; IEA:Compara.
 GO:0007626; P:locomotory behavior; IEA:Compara.
 GO:0045599; P:negative regulation of fat cell differentiation; IEA:Compara.
 GO:0048147; P:negative regulation of fibroblast proliferation; IEA:Compara.
 GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Compara.
 GO:0048666; P:neuron development; IEA:Compara.
 GO:0032364; P:oxygen homeostasis; IEA:Compara.
 GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IEA:Compara.
 GO:0009791; P:post-embryonic development; IEA:Compara.
 GO:0051289; P:protein homotetramerization; IEA:Compara.
 GO:0050790; P:regulation of catalytic activity; IEA:Compara.
 GO:0051881; P:regulation of mitochondrial membrane potential; IEA:Compara.
 GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0001836; P:release of cytochrome c from mitochondria; IEA:Compara.
 GO:0019430; P:removal of superoxide radicals; IEA:Compara.
 GO:0022904; P:respiratory electron transport chain; IEA:Compara.
 GO:0014823; P:response to activity; IEA:Compara.
 GO:0048678; P:response to axon injury; IEA:Compara.
 GO:0010332; P:response to gamma radiation; IEA:Compara.
 GO:0042542; P:response to hydrogen peroxide; IEA:Compara.
 GO:0055093; P:response to hyperoxia; IEA:Compara.
 GO:0042554; P:superoxide anion generation; IEA:Compara.
 GO:0003069; P:vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure; IEA:Compara. 
Interpro
 IPR001189; Mn/Fe_SOD.
 IPR019833; Mn/Fe_SOD_BS.
 IPR019832; Mn/Fe_SOD_C.
 IPR019831; Mn/Fe_SOD_N. 
Pfam
 PF02777; Sod_Fe_C
 PF00081; Sod_Fe_N 
SMART
  
PROSITE
 PS00088; SOD_MN 
PRINTS
 PR01703; MNSODISMTASE.