CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025284
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 Arel1 
Gene Synonyms/Alias
 1110018G07Rik 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
477ALLESSLKATRNFSIubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Ligase; Ubl conjugation pathway. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 823 AA 
Protein Sequence
MFYVIGGIIV SVVAFFFTIK FLFELAARVV SFLQNEDRER RGDRTIYDYV RGNYLDPRSC 60
KVSWDWKDPY EVGHSMAFRV RLFYKNGQPF PAHRPVGLRV HISHVELAVD IPVTQEVLQE 120
PNSNVVKVAF TVRKAGRYEI TVKLGGLNVA YSPYYKIFQP GMVVPSKTKI VCHFSTLVLT 180
CGQPHTLQIV PRDEYDNPTN NSMSLRDEHS YSLAIHELGP QEEENNEVSF EKSVTSNRQT 240
CQVFLRLTLH SRGCFHACIS YQNQPINNGE FDIIVLSENE KNIVERNVST SGVSIYFEAY 300
LYNANNCTST PWHLPPMHMS SSQRRPSTAI EEDDEDSPSE CHTPEKVKKP KKVYCYVSPK 360
QFSVKEFYLK IIPWRLYTFR VCPGTKFSYL GPDPVHKLLT LVVDDGIQPP VELSCKERNI 420
LAATFIRSLH KNIGGSETFQ DKVNFFQREL RQVHMKRPHS KVTLKVSRHA LLESSLKATR 480
NFSISDWSKN FEVVFQDEEA LDWGGPRREW FELICKALFD TTSQLFARFT DSNQALVHPN 540
PNRPAHLRLK MYEFAGRLVG KCLYESSLGG AYKQLVRARF TRSFLAQIIG LRMHYKYFET 600
DDPEFYKSKV CFILNNDMSE MELVFAEEKY NKSGQLDKIV ELMTGGAQTP VTNANKIFYL 660
NLLAQYRLAS QVKEEVEHFL KGLNELVPEN LLAIFDENEL ELLMCGTGDI NVSDFKAHAV 720
VVGGSWHFRE KVMRWFWAVV SSLTQEELAR LLQFTTGSSQ LPPGGFAALC PSFQIIAAPT 780
HSTLPTAHTC FNQLCLPTYD SYEEVHRMLQ LAISEGCEGF GML 823 
Gene Ontology
 GO:0005737; C:cytoplasm; IBA:RefGenome.
 GO:0005634; C:nucleus; IBA:RefGenome.
 GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
 GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. 
Interpro
 IPR001298; Filamin.
 IPR017868; Filamin/ABP280_repeat-like.
 IPR000569; HECT.
 IPR013783; Ig-like_fold.
 IPR014756; Ig_E-set. 
Pfam
 PF00630; Filamin
 PF00632; HECT 
SMART
 SM00119; HECTc
 SM00557; IG_FLMN 
PROSITE
 PS50194; FILAMIN_REPEAT
 PS50237; HECT 
PRINTS