UniProt Accession

 GBG3_HUMAN; P63215; B2R4S7; P29798; Q61014 

Genbank Protein ID

 AF092129; AF188177; AF087900; AF493871; AK311933; CH471076; BC015563 

Genbank Nucleotide ID

 AAD40371.1; AAF04567.1; AAP97199.1; AAM12585.1; BAG34874.1; EAW74082.1; AAH15563.1 

Protein Name

 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 

Protein Synonyms/Alias

  

Gene Name

 GNG3 

Gene Synonyms/Alias

 GNGT3 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
24	RKMVEQLKIEASLCR	methylation	[1]

Reference

 [1] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510] 

Functional Description

 Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. 

Sequence Annotation

 MOD_RES 5 5 Phosphothreonine (By similarity).
 MOD_RES 9 9 Phosphoserine (By similarity).
 MOD_RES 72 72 Cysteine methyl ester (By similarity).
 LIPID 72 72 S-geranylgeranyl cysteine (By  

Keyword

 Cell membrane; Complete proteome; Lipoprotein; Membrane; Methylation; Phosphoprotein; Prenylation; Reference proteome; Transducer. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 75 AA 

Protein Sequence

Gene Ontology

 GO:0005834; C:heterotrimeric G-protein complex; IEA:InterPro.
 GO:0005886; C:plasma membrane; TAS:Reactome.
 GO:0003924; F:GTPase activity; TAS:ProtInc.
 GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
 GO:0000187; P:activation of MAPK activity; TAS:ProtInc.
 GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
 GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
 GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro.
 GO:0007268; P:synaptic transmission; TAS:Reactome. 

Interpro

 IPR015898; G-protein_gamma-like_dom.
 IPR001770; Gprotein-gamma. 

Pfam

 PF00631; G-gamma 

SMART

 SM00224; GGL 

PROSITE

 PS50058; G_PROTEIN_GAMMA 

PRINTS

 PR00321; GPROTEING.