CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024604
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uroplakin-3b-like protein 
Protein Synonyms/Alias
  
Gene Name
 UPK3BL 
Gene Synonyms/Alias
 UPLP 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
148DTHCQPTKIGCNHPLubiquitination[1, 2]
164GPGPYRVKFLVMNDEubiquitination[2, 3, 4]
178EGPVAETKWSSDTRLubiquitination[1, 2, 5]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [4] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [5] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
 CARBOHYD 51 51 N-linked (GlcNAc...) (Potential).
 CARBOHYD 76 76 N-linked (GlcNAc...) (Potential).
 CARBOHYD 91 91 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 263 AA 
Protein Sequence
MDNSWRLGPA IGLSAGQSQL LVSLLLLLTR VQPGTDVAAP EHISYVPQLS NDTLAGRLTL 60
STFTLEQPLG QFSSHNISDL DTIWLVVALS NATQSFTAPR TNQDIPAPAN FSQRGYYLTL 120
RANRVLYQTR GQLHVLRVGN DTHCQPTKIG CNHPLPGPGP YRVKFLVMND EGPVAETKWS 180
SDTRLQQAQA LRAVPGPQSP GTVVIIAILS ILLAVLLTVL LAVLIYTCFN SCRSTSLSGP 240
EEAGSVRRYT THLAFSTPAE GAS 263 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR024831; Uroplakin-3.
 IPR024827; Uroplakin-3b-like. 
Pfam
  
SMART
  
PROSITE
  
PRINTS