| Tag | Content |
|---|
| CPLM ID | CPLM-015229 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Kinesin-like protein KIF15 |
Protein Synonyms/Alias | Kinesin-like protein 2; Kinesin-like protein 7 |
Gene Name | Kif15 |
Gene Synonyms/Alias | Klp2; Knsl7 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 1280 | VQSALHSKEKACHRM | acetylation | [1] |
|
Reference | [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3. Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C. PLoS One. 2012;7(12):e50545. [ PMID: 23236377] |
Functional Description | Plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly (By similarity). |
Sequence Annotation | DOMAIN 23 290 Kinesin-motor.
NP_BIND 109 116 ATP (By similarity).
MOD_RES 568 568 Phosphoserine (By similarity).
MOD_RES 1009 1009 N6-acetyllysine (By similarity).
MOD_RES 1141 1141 Phosphoserine (By similarity).
MOD_RES 1144 1144 Phosphothreonine (By similarity).
MOD_RES 1169 1169 Phosphoserine (By similarity). |
Keyword | Acetylation; ATP-binding; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Motor protein; Nucleotide-binding; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1387 AA |
Protein Sequence | MAPGCKSELR NVTNSHSNQP SNEGDAIKVF VRIRPAEEGA RSADGEQSFC LSVLSQTTLR 60
LHSNPDPKTF VFDYVAGMDT TQESVFSTVA KSIVESCMSG YNGTIFAYGQ TGSGKTFTMM 120
GPSDSDNFSH NLRGIIPRSF EYLFSLIDRE KEKAGAGKSF LCKCSFIEVY NEQIYDLLDS 180
ASVGLYLREH IKKGVFVVGA VEQAVTSAAE TYQVLSRGWR NRRVASTSMN RESSRSHAVF 240
TITIESMEKS SETVNIRTSL LNLVDLAGSE RQKDTHAEGM RLKEAGNINR SLSCLGQVIT 300
ALVDVGNGKQ RHICYRDSKL TFLLRDSLGG NAKTAIIANV HPGSRCFGET LSTLNFAQRA 360
KLIKNKAVVN EDTQGNVSQL QAEVKRLKEQ LSQFTSGQIT PESLLARDKE KTNYIEYFLE 420
AMLFFKKSEQ EKKSLIEKIT QLEDLTLKKE KFIQSNKMIV KFREDQIMRL ERLHKEGRGS 480
FLPEEQDRLL SELRDEVQTL REHVEHHPRL AKYAMENHSL REENRRLKLL APVKRAHEID 540
AQSIARLEKA FAEVSSTETN DKGLQGFSPK ALKESSFFTN TEKLKAQLLQ IQTELNNSKQ 600
EYEEFKELTR KKQLELESEL QSLQKANLNL ENLLEATKVC KRQEVSQLNK LHAETLKIIT 660
TPTKAYQLCS RLVPKSSPEV GSFGFLCTES SSRLDNDILN EPVPPEMSEQ ALEAVSEELR 720
TVQEQLSVLQ VKLDEEERKN LKLQQNVDKL EHHSTQMQEL FSSERSDWTK QQQEHVTQLS 780
DLEKQLQDAQ TKNEFLKCEV HDLRIVLNSA DKELSLVKLE YSTFKENHEK ELSQLSERHV 840
QVQLQLDNAR LENEKLLESQ ACLQDSYDNL QEVMKFEIDQ LSKNLQNCKQ ENETLKSDLH 900
NLVELFEAEK ERNNKLSLQF EEDKENSSKE ILKVLETVRQ EKQKEMAKCE KQMAKIQKLE 960
ESLLATENVI SSLEKSRESD KELVTNLMNQ IQELRISIGE KSETIATLKQ ELQDINCKYN 1020
ASLADKEESK ELIRRQEVDI LELKETLRLR ILSEDIERDM LCEDLAHATE QLNMLTEASK 1080
KHSGLLQSAQ EELTRKEALI QELQHKLNQE KEEVEQKKNE FSLKMRQLEH VMGSATEYPQ 1140
SPKTPPHFQA HLAKLLETQE QEIEDGRASK TSLQHLVTKL NEDREVKNAE ILRMKDQLCE 1200
MENLRLESQQ LREKNWLLQR QLDDVKRQQE SGDQSHPDSQ QLKNEHEEII KERLAKNKLI 1260
EEMLKMKTNL EEVQSALHSK EKACHRMSEE IERTRTLESR AFQEKEQLRS KLEEMYEERE 1320
RTFLEMEMLK KQLEFLAEEN GKLVGHQNLH QKIQYVVRLK KENIRLTEET EKLRAENLFL 1380
KEKKKEF 1387 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005874; C:microtubule; IEA:UniProtKB-KW. GO:0005875; C:microtubule associated complex; IEA:InterPro. GO:0005819; C:spindle; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0003777; F:microtubule motor activity; IEA:InterPro. GO:0007018; P:microtubule-based movement; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |