UniProt Accession

 G3UVW6_MOUSE; G3UVW6 

Genbank Protein ID

 AC102101; AC163998; AC163999; AB643813; CH466581 

Genbank Nucleotide ID

 BAL45579.1; EDL03307.1 

Protein Name

 Prolactin receptor 

Protein Synonyms/Alias

 Prolactin receptor, isoform CRA_b 

Gene Name

 Prlr 

Gene Synonyms/Alias

 prlr; mCG_18319 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
272	PVPGPKIKGFDTHLL	ubiquitination	[1]
286	LETGSPSKYKVDPRL	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Receptor; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 310 AA 

Protein Sequence

Gene Ontology

 GO:0016020; C:membrane; IEA:InterPro.
 GO:0004925; F:prolactin receptor activity; IDA:MGI.
 GO:0007259; P:JAK-STAT cascade; IMP:MGI.
 GO:0007595; P:lactation; IMP:MGI.
 GO:0060749; P:mammary gland alveolus development; IMP:MGI.
 GO:0060644; P:mammary gland epithelial cell differentiation; IGI:MGI.
 GO:0060736; P:prostate gland growth; IMP:MGI.
 GO:0030155; P:regulation of cell adhesion; IMP:MGI.
 GO:0030856; P:regulation of epithelial cell differentiation; IMP:MGI. 

Interpro

 IPR003961; Fibronectin_type3.
 IPR015152; Growth/epo_recpt_lig-bind.
 IPR013783; Ig-like_fold.
 IPR003528; Long_hematopoietin_rcpt_CS. 

Pfam

 PF09067; EpoR_lig-bind
 PF00041; fn3 

SMART

 SM00060; FN3 

PROSITE

 PS50853; FN3
 PS01352; HEMATOPO_REC_L_F1 

PRINTS