CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045409
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Paired amphipathic helix protein Sin3b 
Protein Synonyms/Alias
  
Gene Name
 SIN3B 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
51GQFLPEAKRSLFTGNubiquitination[1, 2, 3, 4]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 309 AA 
Protein Sequence
XLHTYQKEQL NTRGRPFRGM SEEEVFTEVA NLFRGQEDLL SEFGQFLPEA KRSLFTGNGP 60
CEMHSVQKNE HDKTPEHSRK RSRPSLLRPV SAPAKKKMKL RGTKDLSIAA VGKYGTLQEF 120
SFFDKVRRVL KSQEVYENFL RCIALFNQEL VSGSELLQLV SPFLGKFPEL FAQFKSFLGV 180
KELSFAPPMS DRSGDGISRE IDYASCKRIG SSYRALPKTY QQPKCSGRTA ICKELDHWTL 240
LQGSWTDDYC MSKFKNTCWI PGYSAGVSKL WPTGPGPLPV FVNKVLLSHR HNHSFTYCLW 300
LLFSPQRQS 309 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR013194; HDAC_interact.
 IPR003822; PAH. 
Pfam
 PF02671; PAH
 PF08295; Sin3_corepress 
SMART
  
PROSITE
 PS51477; PAH 
PRINTS