UniProt Accession

 F5H3D8_HUMAN; F5H3D8 

Genbank Protein ID

 AP000593 

Genbank Nucleotide ID

  

Protein Name

 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 

Protein Synonyms/Alias

  

Gene Name

 INPPL1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
89	TKIGKSQKFTLSVDV	ubiquitination	[1]

Reference

 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 157 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0030027; C:lamellipodium; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:Compara.
 GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IEA:Compara.
 GO:0007420; P:brain development; IEA:Compara.
 GO:0006006; P:glucose metabolic process; IEA:Compara.
 GO:0032957; P:inositol trisphosphate metabolic process; IEA:Compara.
 GO:0008285; P:negative regulation of cell proliferation; IEA:Compara.
 GO:0008156; P:negative regulation of DNA replication; IEA:Compara.
 GO:0010629; P:negative regulation of gene expression; IEA:Compara.
 GO:0046627; P:negative regulation of insulin receptor signaling pathway; IEA:Compara.
 GO:0043569; P:negative regulation of insulin-like growth factor receptor signaling pathway; IEA:Compara.
 GO:0043407; P:negative regulation of MAP kinase activity; IEA:Compara.
 GO:0010977; P:negative regulation of neuron projection development; IEA:Compara.
 GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; IEA:Compara.
 GO:0006661; P:phosphatidylinositol biosynthetic process; IEA:Compara.
 GO:0009791; P:post-embryonic development; IEA:Compara.
 GO:0042493; P:response to drug; IEA:Compara.
 GO:0032868; P:response to insulin stimulus; IEA:Compara.
 GO:0097178; P:ruffle assembly; IEA:Compara. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS