CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032133
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Kinesin-like protein KIF2C 
Protein Synonyms/Alias
 cDNA FLJ53680, highly similar to Kinesin-like protein KIF2C 
Gene Name
 KIF2C 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
28PAAANSRKQFSVPPAubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Microtubule; Motor protein; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 612 AA 
Protein Sequence
MSTVSELRIT AQENDMEVEL PAAANSRKQF SVPPAPTRPS CPAVAEIPLR MVSEEMEEQV 60
HSIRGSSSAN PVNSVRRKSC LVKEVEKMKN KREEKKAQNS EMRMKRAQEY DSSFPNWEFA 120
RMIKEFRATL ECHPLTMTDP IEEHRICVCV RKRPLNKQEL AKKEIDVISI PSKCLLLVHE 180
PKLKVDLTKY LENQAFCFDF AFDETASNEV VYRFTARPLV QTIFEGGKAT CFAYGQTGSG 240
KTHTMGGDLS GKAQNASKGI YAMASRDVFL LKNQPCYRKL GLEVYVTFFE IYNGKLFDLL 300
NKKAKLRVLE DGKQQVQVVG LQEHLVNSAD DVIKMIDMGS ACRTSGQTFA NSNSSRSHAC 360
FQIILRAKGR MHGKFSLVDL AGNERGADTS SADRQTRMEG AEINKSLLAL KECIRALGQN 420
KAHTPFRESK LTQVLRDSFI GENSRTCMIA TISPGISSCE YTLNTLRYAD RVKELSPHSG 480
PSGEQLIQME TEEMEACSNG ALIPGNLSKE EEELSSQMSS FNEAMTQIRE LEEKAMEELK 540
EIIQQGPDWL ELSEMTEQPD YDLETFVNKA ESALAQQAKH FSALRDVIKA LRLAMQLEEQ 600
ASRQISSKKR PQ 612 
Gene Ontology
 GO:0000775; C:chromosome, centromeric region; IEA:Compara.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005875; C:microtubule associated complex; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003777; F:microtubule motor activity; IEA:InterPro.
 GO:0007018; P:microtubule-based movement; IEA:InterPro. 
Interpro
 IPR019821; Kinesin_motor_CS.
 IPR001752; Kinesin_motor_dom.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00225; Kinesin 
SMART
 SM00129; KISc 
PROSITE
 PS00411; KINESIN_MOTOR_DOMAIN1
 PS50067; KINESIN_MOTOR_DOMAIN2 
PRINTS
 PR00380; KINESINHEAVY.