| Tag | Content |
|---|
| CPLM ID | CPLM-003534 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | NADH-quinone oxidoreductase subunit H |
Protein Synonyms/Alias | NADH dehydrogenase I subunit H; NDH-1 subunit H; NUO8 |
Gene Name | nuoH |
Gene Synonyms/Alias | b2282; JW2277 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 76 | FKEDWIPKFSDRVIF | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. |
Sequence Annotation | |
Keyword | Cell inner membrane; Cell membrane; Complete proteome; Membrane; NAD; Oxidoreductase; Quinone; Reference proteome; Transmembrane; Transmembrane helix; Ubiquinone. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 325 AA |
Protein Sequence | MSWISPELIE ILLTILKAVV ILLVVVTCGA FMSFGERRLL GLFQNRYGPN RVGWGGSLQL 60
VADMIKMFFK EDWIPKFSDR VIFTLAPMIA FTSLLLAFAI VPVSPGWVVA DLNIGILFFL 120
MMAGLAVYAV LFAGWSSNNK YSLLGAMRAS AQTLSYEVFL GLSLMGVVAQ AGSFNMTDIV 180
NSQAHVWNVI PQFFGFITFA IAGVAVCHRH PFDQPEAEQE LADGYHIEYS GMKFGLFFVG 240
EYIGIVTISA LMVTLFFGGW QGPLLPPFIW FALKTAFFMM MFILIRASLP RPRYDQVMSF 300
GWKICLPLTL INLLVTAAVI LWQAQ 325 |
Gene Ontology | GO:0005887; C:integral to plasma membrane; IDA:EcoCyc. GO:0045272; C:plasma membrane respiratory chain complex I; IDA:EcoCyc. GO:0050136; F:NADH dehydrogenase (quinone) activity; IEA:EC. GO:0048038; F:quinone binding; IEA:UniProtKB-KW. GO:0009060; P:aerobic respiration; IMP:EcoCyc. |
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Pfam | |
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PROSITE | |
PRINTS | |