CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014480
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sec1 family domain-containing protein 1 
Protein Synonyms/Alias
 SLY1 homolog; Sly1p; Syntaxin-binding protein 1-like 2; Vesicle transport-related protein Ra410 
Gene Name
 Scfd1 
Gene Synonyms/Alias
 Ra410; Sly1; Stxbp1l2 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
319YDLTPVDKFWQKHKGacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi. 
Sequence Annotation
 MOD_RES 298 298 Phosphoserine (By similarity).  
Keyword
 3D-structure; Complete proteome; Cytoplasm; Direct protein sequencing; Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 637 AA 
Protein Sequence
MVGSKMAASI RERQTVALKR MLNFNVPHVK NSPGEPVWKV LIYDRFGQDI ISPLLSVKEL 60
RDMGITLHLL LHSDRDPIRD VPAVYFVMPT EENIDRLCQD LRNQLYESYY LNFISAISRS 120
KLEDIANAAL AANAVTQVAK VFDQYLNFIT LEEDMFVLCN QNKELVSYRA INRPDITDTE 180
METVMDTIVD SLFCFFVTLG AVPIIRCSRG TAAEMVAVKL DKKLRENLRD ARNSLFTGDP 240
LGTGQFSFQR PLLVLVDRNI DLATPLHHTW TYQALVHDVL DFHLNRVNLE ESTGVENSPT 300
GARPKRKNKK SYDLTPVDKF WQKHKGSPFP EVAESVQQEL ESYRAQEDEV KRLKSIMGLE 360
GEDEGAISML SDNTAKLTSA VSSLPELLEK KRLIDLHTNV ATAVLEHIKA RKLDVYFEYE 420
EKIMSKTTLD KSLLDVISDP DAGTPEDKMR LFLIYYISAQ QAPSEVDLEQ YKKALTDAGC 480
NLSPLQYIKQ WKAFAKMAST PASYGNTTTK PMGLLSRVMN TGSQFVMEGV KNLVLKQQNL 540
PVTRILDNLM EMKSNPETDD YRYFDPKMLR SNDSSVPRNK SPFQEAIVFV VGGGNYIEYQ 600
NLVDYIKGKQ GKHILYGCSE IFNATQFIKQ LSQLGQK 637 
Gene Ontology
 GO:0005801; C:cis-Golgi network; IEA:Compara.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
 GO:0005798; C:Golgi-associated vesicle; IDA:RGD.
 GO:0005886; C:plasma membrane; IDA:RGD.
 GO:0019905; F:syntaxin binding; IDA:RGD.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:RGD.
 GO:0006892; P:post-Golgi vesicle-mediated transport; IDA:RGD.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IMP:RGD.
 GO:0001666; P:response to hypoxia; IEP:RGD.
 GO:0009636; P:response to toxic substance; IEA:Compara.
 GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IMP:UniProtKB.
 GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro. 
Interpro
 IPR027482; Sec-1-like_dom2.
 IPR001619; Sec1-like. 
Pfam
 PF00995; Sec1 
SMART
  
PROSITE
  
PRINTS