UniProt Accession

 CAB39_MOUSE; Q06138; Q8VDZ8 

Genbank Protein ID

 S51858; AK144665; CH466520; CH466520; CH466520; BC020041 

Genbank Nucleotide ID

 AAB24801.1; BAE25997.1; EDL40253.1; EDL40254.1; EDL40256.1; AAH20041.1 

Protein Name

 Calcium-binding protein 39 

Protein Synonyms/Alias

 MO25alpha; Protein Mo25 

Gene Name

 Cab39 

Gene Synonyms/Alias

 Mo25 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
17	KSPADIVKNLKESMA	ubiquitination	[1]
196	KDLLTRHKLLSAEFL	acetylation	[2]
216	RFFSEYEKLLHSENY	ubiquitination	[1]
297	PILDILLKNQTKLIE	ubiquitination	[1]
301	ILLKNQTKLIEFLSK	acetylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

 Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1 (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; Cytoplasm; Direct protein sequencing; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 341 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005509; F:calcium ion binding; ISS:MGI.
 GO:0030295; F:protein kinase activator activity; ISS:UniProtKB.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:Compara. 

Interpro

 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR013878; Mo25. 

Pfam

 PF08569; Mo25 

SMART

  

PROSITE

  

PRINTS