CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036914
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 NACHT, LRR and PYD domains-containing protein 7 
Protein Synonyms/Alias
  
Gene Name
 NLRP7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
560LANEKRAKELEATFGubiquitination[1]
845YKTMTRPKHFLQMLSubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1065 AA 
Protein Sequence
MSRKHRLEAR PDLREFFSLN LRSHTRSTMT SPQLEWTLQT LLEQLNEDEL KSFKSLLWAF 60
PLEDVLQKTP WSEVEEADGK KLAEILVNTS SENWIRNATV NILEEMNLTE LCKMAKAEMM 120
EDGQVQEIDN PELGDAEEDS ELAKPGEKEG WRNSMEKQSL VWKNTFWQGD IDNFHDDVTL 180
RNQRFIPFLN PRTPRKLTPY TVVLHGPAGV GKTTLAKKCM LDWTDCNLSP TLRYAFYLSC 240
KELSRMGPCS FAELISKDWP ELQDDIPSIL AQAQRILFVV DGLDELKVPP GALIQDICGD 300
WEKKKPVPVL LGSLLKRKML PRAALLVTTR PRALRDLQLL AQQPIYVRVE GFLEEDRRAY 360
FLRHFGDEDQ AMRAFELMRS NAALFQLGSA PAVCWIVCTT LKLQMEKGED PVPTCLTRTG 420
LFLRFLCSRF PQGAQLRGAL RTLSLLAAQG LWAQMSVFHR EDLERLGVQE SDLRLFLDGD 480
ILRQDRVSKG CYSFIHLSFQ QFLTALFYAL EKEEGEDRDG HAWDIGDVQK LLSGEERLKN 540
PDLIQVGHFL FGLANEKRAK ELEATFGCRM SPDIKQELLQ CKAHLHANKP LSVTDLKEVL 600
GCLYESQEEE LAKVVVAPFK EISIHLTNTS EVMHCSFSLK HCQDLQKLSL QVAKGVFLEN 660
YMDFELDIEF ERCTYLTIPN WARQDLRSLR LWTDFCSLFS SNSNLKFLEV KQSFLSDSSV 720
RILCDHVTRS TCHLQKVEIK NVTPDTAYRD FCLAFIGKKT LTHLTLAGHI EWERTMMLML 780
CDLLRNHKCN LQYLRLGGHC ATPEQWAEFF YVLKANQSLK HLRLSANVLL DEGAMLLYKT 840
MTRPKHFLQM LSLENCRLTE ASCKDLAAVL VVSKKLTHLC LAKNPIGDTG VKFLCEGLSY 900
PDCKLQTLVL QQCSITKLGC RYLSEALQEA CSLTNLDLSI NQIARGLWIL CQALENPNCN 960
LKHLRLWSCS LMPFYCQHLG SALLSNQKLE TLDLGQNHLW KSGIIKLFGV LRQRTGSLKI 1020
LRLKTYETNL EIKKLLEEVK EKNPKLTIDC NASGATAPPC CDFFC 1065 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW. 
Interpro
 IPR004020; DAPIN.
 IPR011029; DEATH-like_dom.
 IPR007111; NACHT_NTPase.
 IPR027417; P-loop_NTPase. 
Pfam
 PF02758; PYRIN 
SMART
  
PROSITE
 PS50824; DAPIN
 PS50837; NACHT 
PRINTS