CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007443
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phosphoenolpyruvate carboxykinase [ATP] 
Protein Synonyms/Alias
 PEP carboxykinase; PEPCK; Phosphoenolpyruvate carboxylase 
Gene Name
 pckA 
Gene Synonyms/Alias
 pck; STM3500 
Created Date
 July 27, 2013 
Organism
 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 
NCBI Taxa ID
 99287 
Lysine Modification
Position
Peptide
Type
References
86DTLWWSDKGKGKNDNacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
  
Sequence Annotation
 NP_BIND 247 254 ATP (By similarity).  
Keyword
 Allosteric enzyme; ATP-binding; Calcium; Complete proteome; Cytoplasm; Decarboxylase; Gluconeogenesis; Lyase; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 538 AA 
Protein Sequence
MRVNNLTPQD LKAYGINDVQ DIVYNPSYDT LYQEELNPGL EGYERGVLTN LGAVAVDTGI 60
FTGRSPKDKY IVRDDTTRDT LWWSDKGKGK NDNKPLSQET WQHLKGLVTH QLSGKRLFIV 120
DAFCGANADT RLSVRFITEV AWQAHFVKNM FIRPTDEELV GFKPDFIVMN GAKCTNPQWK 180
EQGLNSENFV AFNLTERIQL IGGTWYGGEM KKGMFSVMNY LLPLKGIASM HCSANVGEKG 240
DVAVFFGLSG TGKTTLSTDP KRRLIGDDEH GWDDDGVFNF EGGCYAKTIK LSKEAEPEIY 300
HAIRRDALLE NVTVREDGTV DFDDGSKTEN TRVSYPIYHI DNIVKPVSKA GHATKVIFLT 360
ADFGVLPPVS RLTANQTQYH FLSGFTAKLA GTERGVTEPT PTFSACFGAA FLTLHPTQYA 420
EVLVKRMQAA GAQAYLVNTG WNGTGKRISI KDTRAIIDAI LNGSLDNAET FRLPLFDLAI 480
PTELPGVDTH ILDPRNTYAS PEQWQEKATA LAKLFIENFE KYTDTPAGEA LVSAGPKL 538 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0004612; F:phosphoenolpyruvate carboxykinase (ATP) activity; IEA:HAMAP.
 GO:0006094; P:gluconeogenesis; IEA:HAMAP. 
Interpro
 IPR001272; PEP_carboxykinase_ATP.
 IPR013035; PEP_carboxykinase_C.
 IPR008210; PEP_carboxykinase_N.
 IPR015994; PEPCK_ATP_CS. 
Pfam
 PF01293; PEPCK_ATP 
SMART
  
PROSITE
 PS00532; PEPCK_ATP 
PRINTS