UniProt Accession

 B4E175_HUMAN; B4E175 

Genbank Protein ID

 AK303701 

Genbank Nucleotide ID

 BAG64687.1 

Protein Name

 cDNA FLJ54775, highly similar to Syntaxin-binding protein 2 

Protein Synonyms/Alias

  

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
13	LKAVVGEKILSGVIR	ubiquitination	[1, 2, 3]
100	QSVQALIKDFQGTPT	ubiquitination	[2, 3]
219	LAHAVLAKLNAFKAD	ubiquitination	[3]
331	SKRLTTDKANIKDLS	ubiquitination	[3]
335	TTDKANIKDLSQILK	ubiquitination	[2, 3]
571	VTRATEGKWEVLIGS	ubiquitination	[3]

Reference

 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

  

Keyword

  

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 604 AA 

Protein Sequence

Gene Ontology

 GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro. 

Interpro

 IPR027482; Sec-1-like_dom2.
 IPR001619; Sec1-like. 

Pfam

 PF00995; Sec1 

SMART

  

PROSITE

  

PRINTS