| Tag | Content |
|---|
| CPLM ID | CPLM-008701 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Histone H1 |
Protein Synonyms/Alias | |
Gene Name | HHO1 |
Gene Synonyms/Alias | YPL127C; LPI17C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 186 | TYKEMILKSMPQLND | acetylation | [1] | | 207 | IVLKKYVKDTFSSKL | acetylation | [1] | | 213 | VKDTFSSKLKTSSNF | acetylation | [1] | | 229 | YLFNSAIKKCVENGE | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Could act as an H1-type linker histone. Has been shown to bind DNA. |
Sequence Annotation | DOMAIN 43 117 H15 1.
DOMAIN 176 251 H15 2.
MOD_RES 174 174 Phosphoserine. |
Keyword | 3D-structure; Chromosome; Complete proteome; DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 258 AA |
Protein Sequence | MAPKKSTTKT TSKGKKPATS KGKEKSTSKA AIKKTTAKKE EASSKSYREL IIEGLTALKE 60
RKGSSRPALK KFIKENYPIV GSASNFDLYF NNAIKKGVEA GDFEQPKGPA GAVKLAKKKS 120
PEVKKEKEVS PKPKQAATSV SATASKAKAA STKLAPKKVV KKKSPTVTAK KASSPSSLTY 180
KEMILKSMPQ LNDGKGSSRI VLKKYVKDTF SSKLKTSSNF DYLFNSAIKK CVENGELVQP 240
KGPSGIIKLN KKKVKLST 258 |
Gene Ontology | GO:0000788; C:nuclear nucleosome; IPI:SGD. GO:0003677; F:DNA binding; IPI:SGD. GO:0031936; P:negative regulation of chromatin silencing; IGI:SGD. GO:0045910; P:negative regulation of DNA recombination; IGI:SGD. GO:0006334; P:nucleosome assembly; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |