CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008834
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Erythrocyte band 7 integral membrane protein 
Protein Synonyms/Alias
 Protein 7.2b; Stomatin 
Gene Name
 Stom 
Gene Synonyms/Alias
 Epb7.2; Epb72 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
198RVEIKDVKLPVQLQRubiquitination[1]
220AAREARAKVIAAEGEubiquitination[1]
235MNASRALKEASMVITubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Thought to regulate cation conductance. May regulate ASIC2 and ASIC3 gating. 
Sequence Annotation
 REGION 265 273 Required for homooligomerization (By
 REGION 267 269 Required for lipid raft association (By
 REGION 273 284 Interaction with LANCL1 (By similarity).
 MOD_RES 161 161 Phosphoserine.
 MOD_RES 244 244 Phosphoserine.
 LIPID 30 30 S-palmitoyl cysteine (By similarity).
 LIPID 87 87 S-palmitoyl cysteine (By similarity).  
Keyword
 3D-structure; Cell membrane; Complete proteome; Lipoprotein; Membrane; Palmitate; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 284 AA 
Protein Sequence
MSDKRQSSHV QSQRIPESFR ENSKTELGAC GWILVAASFF FVIITFPISI WICIKIVKEY 60
ERVIIFRLGR ILQGGAKGPG LFFILPCTDS LIKVDMRTIS FDIPPQEVLT KDSVTISVDG 120
VVYYRVQNAT LAVANITNAD SATRLLAQTT LRNALGTKNL SQILSDREEI AHHMQSTLDD 180
ATDDWGIKVE RVEIKDVKLP VQLQRAMAAE AEAAREARAK VIAAEGEMNA SRALKEASMV 240
ITESPAALQL RYLQTLTTIA AEKNSTIVFP LPVDMLQGIM GSNH 284 
Gene Ontology
 GO:0005856; C:cytoskeleton; ISS:UniProtKB.
 GO:0070062; C:extracellular vesicular exosome; IEA:Compara.
 GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.
 GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
 GO:0045121; C:membrane raft; ISS:UniProtKB.
 GO:0051260; P:protein homooligomerization; ISS:UniProtKB. 
Interpro
 IPR001107; Band_7.
 IPR018080; Band_7/stomatin-like_CS.
 IPR001972; Stomatin. 
Pfam
 PF01145; Band_7 
SMART
 SM00244; PHB 
PROSITE
 PS01270; BAND_7 
PRINTS
 PR00721; STOMATIN.